Alfred Kwesi Manyeh

University of Health and Allied Sciences

63 publications · 1,067 citations · ORCID 0000-0002-7005-5707

Global Maternal and Child HealthParasites and Host InteractionsParasitic Diseases Research and TreatmentMalaria Research and ControlChild Nutrition and Water Access

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Alfred Kwesi Manyeh is a public health researcher specializing in epidemiology, implementation science, and the control of Neglected Tropical Diseases (NTDs), with a specific focus on schistosomiasis and lymphatic filariasis in Ghana. Manyeh employs mixed-methods and spatial modeling approaches to evaluate disease burden, health system readiness, and the effectiveness of mass drug administration interventions. The research portfolio also encompasses maternal and child health, analyzing determinants of service utilization such as caesarean sections, breastfeeding, and vaccination.

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How do specific cultural beliefs regarding 'insufficient milk' in rural South African communities mediate the relationship between maternal dietary diversity and the introduction of prelacteal feeds?

Why this gap exists: While the retrieved papers discuss general breastfeeding barriers in South Africa [8] and cultural influences in other regions like Ethiopia [6] and Malaysia [9], none specifically address the mediation of 'insufficient milk' beliefs on the relationship between maternal dietary diversity and prelacteal feeds in rural South African communities.

Sources

African Political Systems. — American Sociological Review, 1940
Maternal nutrition counselling is associated with reduced stunting prevalence and improved feeding practices in early childhood: a post-program comparison study — Nutrition Journal, 2019
Trends and determinants of early initiation of breastfeeding and exclusive breastfeeding in Ethiopia from 2000 to 2016 — International Breastfeeding Journal, 2019
Marketing of commercial milk formula: a system to capture parents, communities, science, and policy — The Lancet, 2023
Facilitators, barriers, and factors determining the willingness to donate human milk among postpartum mothers in a tertiary women's hospital in Nepal: a cross-sectional study. — International breastfeeding journal, 2026
Assessment of Infant and Young Child Feeding Practices among Mothers Attending Maternal and Child Health Clinic at a Tertiary Hospital, North Karnataka, India - A Cross-sectional Study. — Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine, 2025
Sociocultural and structural influences on infant and young child feeding in pastoralist communities of Afar, Ethiopia: a qualitative phenomenological study. — BMJ open, 2026
Knowledge, attitude, and practice of exclusive breastfeeding among mothers in East Africa: a systematic review — International Breastfeeding Journal, 2020
Facilitators and barriers associated with breastfeeding among mothers attending primary healthcare facilities in Mpumalanga, South Africa. — Frontiers in nutrition, 2023
Assessing the Influence of Cultural Beliefs and Practices on Early Breastfeeding Initiation Rates in Rural Sarawak Communities, Malaysia — Scientific Journal of Pediatrics, 2023

To what extent does maternal access to improved water and sanitation facilities mediate the relationship between maternal undernutrition and child developmental outcomes during the first 1,000 days?

Why this gap exists: While the retrieved papers confirm the individual importance of WASH access for child nutrition [0], maternal undernutrition for child development [5, 8], and the critical nature of the first 1,000 days [5], none of the provided abstracts directly analyze the specific mediating role of water and sanitation facilities in the relationship between maternal undernutrition and child developmental outcomes.

Sources

Household water, sanitation, and hygiene access and its impact on nutritional outcomes in children under five: evidence from Pakistan. — BMC public health, 2026
Early childhood development and stunting: Findings from the MAL‐ED birth cohort study in Bangladesh — Maternal and Child Nutrition, 2019
Policy and Structural Drivers of Malnutrition in Afghan Women: Evidence and Interventions. — International journal of women's health, 2026
COVID-19 pandemic and mitigation strategies: implications for maternal and child health and nutrition — American Journal of Clinical Nutrition, 2020
Maternal and child undernutrition 3: what works? Interventions for maternal and child undernutrition and survival — Child: Care, Health and Development, 2008
Nutrition as the Foundation of Human Capital: Pathways to Holistic Development. — Maternal & child nutrition, 2026
The impacts of maternal iron deficiency and being overweight during pregnancy on neurodevelopment of the offspring. — The British journal of nutrition, 2017
Early estimates of the indirect effects of the COVID-19 pandemic on maternal and child mortality in low-income and middle-income countries: a modelling study — The Lancet Global Health, 2020
Prevalence of undernutrition and its associated factors among pregnant women attending antenatal care service in public hospitals in Mogadishu, Somalia. — PloS one, 2026
Concurrent wasting and stunting among under‐five children in Niakhar, Senegal — Maternal & Child Nutrition, 2018

What is the comparative efficacy of household water treatment interventions versus improved water source infrastructure in reducing stunting among children under five in low- and middle-income countries?

Why this gap exists: While the retrieved literature confirms associations between water quality and child growth (e.g., Abstracts 2, 5, 8), no study directly compares the efficacy of household water treatment interventions against improved water source infrastructure for reducing stunting, leaving the specific comparative question unresolved.

Sources

Determinants of stunting in Indonesian children: evidence from a cross-sectional survey indicate a prominent role for the water, sanitation and hygiene sector in stunting reduction — BMC Public Health, 2016
Early estimates of the indirect effects of the COVID-19 pandemic on maternal and child mortality in low-income and middle-income countries: a modelling study — The Lancet Global Health, 2020
Effects of water quality, sanitation, handwashing, and nutritional interventions on diarrhoea and child growth in rural Kenya: a cluster-randomised controlled trial — The Lancet Global Health, 2018
Effects of Water Pollution on Human Health and Disease Heterogeneity: A Review — Frontiers in Environmental Science, 2022
Associated factors with malnutrition among children under-5 years old in Somaliland: evidence from Somaliland health and demographic survey of 2020. — BMC public health, 2026
Safe Drinking Water and Its Impact on Children's Growth and Development: A Systematic Review. — International journal of environmental research and public health, 2026
Modelling the impact of dietary diversity on child nutrition in Pakistan: a machine learning analysis with Shapley Additive exPlanations and Boruta interpretability. — Journal of global health, 2026
Effectiveness of interventions to improve drinking water, sanitation, and handwashing with soap on risk of diarrhoeal disease in children in low-income and middle-income settings: a systematic review and meta-analysis — The Lancet, 2022
Effect of Household Source of Drinking Water on Malnutrition among under Five Children in Ethiopia: Systematic Review and Meta-Analysis — 2026
Water Bridging Dynamics of Polymerase Chain Reaction in the Gauge Theory Paradigm of Quantum Fields — Water 2017, 9, 339, 2018

How do specific maternal microbiota profiles (gut, oral, or vaginal) during gestation correlate with the development of gestational diabetes mellitus (GDM) and subsequent long-term metabolic health in offspring?

Why this gap exists: While recent reviews [8] confirm GDM alters maternal gut microbiota and neonatal health, and older studies [0] note dysbiosis across maternal sites, the retrieved evidence lacks direct, longitudinal studies correlating specific gestational maternal microbiota profiles with the *long-term* metabolic health of offspring, leaving the core question unresolved.

Sources

Dysbiosis of maternal and neonatal microbiota associated with gestational diabetes mellitus — Gut, 2018
Dysbiosis of the gut microbiota in disease — Microbial Ecology in Health and Disease, 2015
Temporal development of the gut microbiome in early childhood from the TEDDY study — Nature, 2018
Microbiota in health and diseases — Signal Transduction and Targeted Therapy, 2022
Maternal Gestational Diabetes Mellitus and Congenital Heart Disease in Offspring: A Meta-Analysis — Hormone and Metabolic Research, 2024
Perinatal phlorizin alleviates maternal high-fat diet-induced metabolic syndrome in female mouse offspring and is associated with modulation of the gut microbiota. — Frontiers in nutrition, 2026
Offspring long-term infectious morbidity following pregnancies with cervical cerclage. — Archives of gynecology and obstetrics, 2026
Interaction between microbiota and immunity in health and disease — Cell Research, 2020
Gestational diabetes mellitus and maternal-infant microbiome axis: mechanistic insights and therapeutic interventions. — Journal of translational medicine, 2026
Microbes in the Moonlight: How the Gut Microbiota Influences Sleep — arXiv preprint, 2025

What is the comparative effectiveness of telemedicine versus traditional in-person care in maintaining essential antenatal coverage and reducing maternal mortality in low-income and middle-income countries during future health system shocks?

Why this gap exists: While abstracts [4], [7], [8], and [9] discuss digital tools and maternity care in low- and middle-income countries, none provide a direct comparative effectiveness analysis of telemedicine versus in-person care regarding maternal mortality during health system shocks, leaving the specific question unresolved.

Sources

COVID-19 and resilience of healthcare systems in ten countries — Nature Medicine, 2022
Community Health Workers Can Provide Psychosocial Support to the People During COVID-19 and Beyond in Low- and Middle- Income Countries — Frontiers in Public Health, 2021
Social Impacts and Responses Related to COVID-19 in Low- and Middle-income Countries — OpenDocs (Institute of Development Studies), 2020
Seizing the moment to rethink health systems — The Lancet Global Health, 2021
Use of mHealth in promoting maternal and child health in “BIMARU” states of India “A health system strengthening strategy”: Systematic literature review — PLOS Digital Health, 2024
Investments for effective functionality of health systems towards Universal Health Coverage in Africa: A scoping review — PLOS Global Public Health, 2022
Infant and young child feeding — OECD eBooks, 2023
Facilitators and barriers to the implementation of a Mobile Health Wallet for pregnancy-related health care: A qualitative study of stakeholders’ perceptions in Madagascar — PLoS ONE, 2020
The impact of digital interventions on health insurance coverage for reproductive, maternal, newborn and child health services utilization in Kakamega, Kenya: a cluster randomized controlled trial — Health Policy and Planning, 2024
Seeking digital maternity healthcare during the pandemic health system shock: a systematic review of women's experiences in low- and middle-income countries — Frontiers in Reproductive Health, 2026

What is the comparative efficacy and cost-effectiveness of the one-step 75g OGTT versus the two-step (50g GCT followed by 100g OGTT) diagnostic approach in preventing adverse maternal and neonatal outcomes?

Why this gap exists: While Abstract [7] compares diagnostic criteria and Abstract [4] compares 75g and 100g OGTTs, the retrieved evidence lacks direct, comparative studies on the cost-effectiveness and relative efficacy of the one-step versus two-step *approaches* in preventing adverse outcomes, leaving the specific question unresolved.

Sources

Glucose Intolerance after a Recent History of Gestational Diabetes Based on the 2013 WHO Criteria — PLoS ONE, 2016
A Multicenter, Randomized Trial of Treatment for Mild Gestational Diabetes — New England Journal of Medicine, 2009
Standards of Medical Care in Diabetes—2013 — Diabetes Care, 2012
An Update on Screening Strategies for Gestational Diabetes Mellitus: A Narrative Review — Diabetes Metabolic Syndrome and Obesity, 2021
Comparison between 75-g and 100-g oral glucose tolerance tests using international association of diabetes and pregnancy study group one-step diagnostic threshold to detect gestational diabetes mellitus — Frontiers in Endocrinology, 2025
Large language models for generating longitudinal synthetic data in low-risk pregnancy care. — Data in brief, 2026
Effects of physical activity and diet in pregnancy to prevent gestational diabetes: an individual participant data (IPD) meta-analysis on the differential effects of interventions with economic evaluation. — Health technology assessment (Winchester, England), 2026
187-OR: Randomized Clinical Trial of the IADPSG vs. Carpenter Coustan Criteria for Diagnosis of Gestational Diabetes Mellitus — Diabetes, 2020
Prevalence of gestational diabetes mellitus and results of the screening tests at a tertiary referral center: A cross-sectional study. — Diabetes & metabolic syndrome, 2019
Gestational Diabetes in Somali Women: Neglected Risks for Maternal and Neonatal Health. — International journal of women's health, 2026

Publications

Exploring the consequences of female genital schistosomiasis among women in endemic districts in Southern Ghana: a phenomenological study using photovoice methodology

BMC Women s Health · 2026

High-resolution mapping of onchocerciasis risk in Ghana using spatial machine learning models

BMC Infectious Diseases · 2026 · corresponding author

The Burden of Male Genital Schistosomiasis in Sub-Saharan Africa- A scoping review

OSF Preprints (OSF Preprints) · 2026

Advances in Public Health · 2026

Reproductive Health Care Infrastructure, Workforce, and Service Delivery Gaps for the Integration of Female Genital Schistosomiasis Services: A Scoping Review

Open MIND · 2026

Facilitators and Barriers to the Uptake of the Med Safety App for Reporting Adverse Drug Reactions in Ghana: A Mixed-Methods Approach

Drugs & Therapy Perspectives · 2026

Current state and future directions of interventions for neglected tropical diseases

Nature Human Behaviour · 2025 · 5 citations

Female genital schistosomiasis in Ghana: An exploration of knowledge, attitudes, and practice among women of reproductive age

Public Health in Practice · 2025 · 1 citations

Systemic and Capacity barriers to Female Genital Schistosomiasis management among healthcare workers in Ghana: A Mixed-Method Approach

Research Square · 2025

Systemic and capacity barriers to female genital schistosomiasis management among healthcare workers in Ghana: a mixed-method approach

Tropical Diseases Travel Medicine and Vaccines · 2025

Evaluating a quality improvement intervention for schistosomiasis mass drug administration in Ghana using the RE-AIM framework

Epidemiology and Infection · 2025

Implementation science in Africa—whose epistemology counts?

The Lancet Global Health · 2025

Assessing knowledge, attitude and preventive practices of schistosomiasis among nursing and midwifery students in the Hohoe nursing and midwifery training college, Ghana

Frontiers in Tropical Diseases · 2025

Gender differences and factors affecting opinions on condom use and sexual experiences among adolescents in a high teenage pregnancy setting in the Volta Region, Ghana

Reproductive Health · 2025

Tailoring interventions for impact: implementing evidence-based strategies for female genital schistosomiasis knowledge gaps in selected districts in Ghana

Frontiers in Tropical Diseases · 2025

The effects of selected neglected tropical diseases on economic performance at the macrolevel in Africa

BMC Infectious Diseases · 2024 · 10 citations

Breaking the silence of female genital schistosomiasis in Ghana’s health system: A case of health workers within the FAST project

PLoS neglected tropical diseases · 2024 · 9 citations

The economic burden of leprosy treatment to households in Ghana: A cross-sectional study in the Volta Region of Ghana

SAGE Open Medicine · 2024 · 5 citations

Assessing five-year trend and socio-demographic determinants of caesarean section delivery in Ghana

BMC Pregnancy and Childbirth · 2024 · corresponding author · 5 citations

The hidden burden of female genital schistosomiasis: a cross-sectional study of knowledge, attitudes, and practices in Ghanaian communities

Frontiers in Tropical Diseases · 2024 · corresponding author · 4 citations

The Social and Economic Impact of Neglected Tropical Diseases in Sub-Saharan Africa

Neglected tropical diseases · 2024 · 4 citations

An empirical analysis of the effects of schistosomiasis and lymphatic filariasis on macroeconomic output in Ghana

Clinical Epidemiology and Global Health · 2024 · 4 citations

Knowledge and management of female genital schistosomiasis in sub-Saharan Africa: A scoping review protocol

Southern African Journal of Infectious Diseases · 2024 · 2 citations

Schistosomiasis

Neglected tropical diseases · 2024 · 1 citations

Assessing five-year trend and socio-demographic determinants of caesarean section delivery in Ghana

Research Square · 2024

Prevalence, trends and associated factors of malaria in the Shai-Osudoku District Hospital, Ghana

Malaria Journal · 2023 · corresponding author · 24 citations

Examining confidence and hesitancy towards COVID-19 vaccines: A cross-sectional survey using in-person data collection in rural Ghana

Vaccine · 2023 · 19 citations

PA-206 Breaking the silence of female genital schistosomiasis in Ghana’s health system: a case of health workers within the FAST project

2023 · 2 citations

Prevalence, trend and associated factors of malaria in the Shai-Osudoku District Hospital

Research Square · 2023

Mixed effect analysis of factors influencing the use of insecticides treated bed nets among pregnant women in Ghana: evidence from the 2019 Malaria Indicator Survey

BMC Pregnancy and Childbirth · 2022 · 24 citations

Determinants of willingness to accept child vaccination against malaria in Ghana

The International Journal of Health Planning and Management · 2022 · 23 citations

Sexual behaviours and their associated factors among young people in the Dodowa Health and Demographic Surveillance Site (DHDSS) in Ghana

Ghana Medical Journal · 2022 · 3 citations

Considering How Best to Allocate Limited Resources for Healthcare in Lower-Income Settings–Reflections on Ghanaian Community-Led Data Collection

International Journal of Public Health · 2022 · 2 citations

Factors Influencing Children Under-Five Immunization Coverage and Acceptance among Mothers and Caregivers in the Hohoe Municipality of Ghana

Research Square · 2022 · 1 citations

COVID-19 vaccine hesitancy among the adult population in Ghana: evidence from a pre-vaccination rollout survey

Tropical Medicine and Health · 2021 · 73 citations

Neonatal mortality rates, characteristics, and risk factors for neonatal deaths in Ghana: analyses of data from two health and demographic surveillance systems

Global Health Action · 2021 · 42 citations

Urban health nexus with coronavirus disease 2019 (COVID-19) preparedness and response in Africa: Rapid scoping review of the early evidence

SAGE Open Medicine · 2021 · 19 citations

Health-seeking behaviour and cost of fever treatment to households in a malaria-endemic setting of northern Ghana: a cross-sectional study

BMJ Open · 2021 · 15 citations

Evaluating context-specific evidence-based quality improvement intervention on lymphatic filariasis mass drug administration in Northern Ghana using the RE-AIM framework

Tropical Medicine and Health · 2021 · corresponding author · 10 citations

Correction: Exploring factors affecting quality implementation of lymphatic filariasis mass drug administration in Bole and Central Gonja Districts in Northern Ghana

PLoS neglected tropical diseases · 2021 · 2 citations

Additional file 1 of COVID-19 vaccine hesitancy among the adult population in Ghana: evidence from a pre-vaccination rollout survey

Figshare · 2021

Towards elimination of lymphatic filariasis in Ghana: refining the strategy through quality improvement

2021 · corresponding author

Factors associated with the timing of antenatal clinic attendance among first-time mothers in rural southern Ghana

BMC Pregnancy and Childbirth · 2020 · corresponding author · 115 citations

Estimating the rate and determinants of exclusive breastfeeding practices among rural mothers in Southern Ghana

International Breastfeeding Journal · 2020 · corresponding author · 57 citations

Exploring factors affecting quality implementation of lymphatic filariasis mass drug administration in Bole and Central Gonja Districts in Northern Ghana

PLoS neglected tropical diseases · 2020 · corresponding author · 36 citations

Determinants of Choice of Abortion Methods among Women in Ghana; Does Knowledge on legality of Abortion Matter?

medRxiv · 2020 · 2 citations

Evaluating Context-Specific Evidence-Based Quality Improvement Intervention on Lymphatic Filariasis Mass Drug Administration in Northern Ghana Using the RE-AIM Framework.

2020 · corresponding author

Evaluating context-specific evidence-based quality improvement intervention on lymphatic filariasis mass drug administration in Northern Ghana using the RE-AIM framework

2020 · corresponding author

Evaluating Context-Specific Evidence-Based Quality Improvement Intervention on Lymphatic Filariasis Mass Drug Administration in Northern Ghana using the RE-AIM Framework.

Research Square (Research Square) · 2020

Using intervention mapping to design and implement quality improvement strategies towards elimination of lymphatic filariasis in Northern Ghana

PLoS neglected tropical diseases · 2019 · corresponding author · 15 citations

Estimating the rate and determinants of exclusive breastfeeding practices among rural mothers in Southern Ghana

bioRxiv (Cold Spring Harbor Laboratory) · 2019 · corresponding author · 12 citations

Correction to: Socioeconomic and demographic factors associated with caesarean section delivery in Southern Ghana: evidence from INDEPTH Network member site

BMC Pregnancy and Childbirth · 2019 · corresponding author · 3 citations

Socioeconomic and demographic factors associated with caesarean section delivery in Southern Ghana: evidence from INDEPTH Network member site

BMC Pregnancy and Childbirth · 2018 · corresponding author · 87 citations

Determinants of access to improved sanitation facilities in rural districts of southern Ghana: evidence from Dodowa Health and Demographic Surveillance Site

BMC Research Notes · 2018 · 69 citations

Maternal mortality in Ifakara Health and Demographic Surveillance System: Spatial patterns, trends and risk factors, 2006 – 2010

PLoS ONE · 2018 · corresponding author · 35 citations

Socio-demographic determinants of skilled birth attendant at delivery in rural southern Ghana

BMC Research Notes · 2017 · corresponding author · 59 citations

Socio-Demographic Determinants of Improved Sources of Domestic Water used by Households in Rural Southern Ghana: Evidence from INDEPTH Network Member Site

International Journal of Trend in Scientific Research and Development · 2017

Socioeconomic and demographic determinants of birth weight in southern rural Ghana: evidence from Dodowa Health and Demographic Surveillance System

BMC Pregnancy and Childbirth · 2016 · corresponding author · 96 citations

Evaluation of a universal long-lasting insecticidal net (LLIN) distribution campaign in Ghana: cost effectiveness of distribution and hang-up activities

Malaria Journal · 2014 · 55 citations

Mortality from external causes in Africa and Asia: evidence from INDEPTH Health and Demographic Surveillance System Sites

Global Health Action · 2014 · 43 citations

Estimating cause of adult (15+ years) death using InterVA-4 in a rural district of southern Ghana

Global Health Action · 2014 · 20 citations

Profile: The Dodowa HDSS

International Journal of Epidemiology · 2013 · 55 citations

Spatial patterns and trends of maternal mortality over a five year period and their associated risk factors in Ifakara Health and Demographic Surveillance Site (IHDSS)

University of the Witwatersrand, Johannesburg Institutional Repository on DSpace (University of the Witwatersrand, Johannesburg) · 2013 · corresponding author