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Francis Ackah Armah

University of Cape Coast

55 publications · 496 citations · ORCID 0000-0001-6560-1147

Ethnobotanical and Medicinal Plants StudiesPharmacological Effects of Natural CompoundsZiziphus Jujuba Studies and ApplicationsMalaria Research and ControlEssential Oils and Antimicrobial Activity

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Francis Ackah Armah is a pharmacologist and natural product researcher focused on validating the therapeutic potential of African medicinal plants. Armah specializes in isolating bioactive compounds, particularly alkaloids, to treat infectious and non-communicable diseases, while also developing quality control standards for herbal products.

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How does the consumption of plant-based proteins, specifically those high in anti-nutritional factors like phytates and trypsin inhibitors, affect mineral bioavailability and growth outcomes in children relying on these proteins as primary staples?

Why this gap exists: While the retrieved papers confirm that anti-nutritional factors like phytates and trypsin inhibitors reduce mineral bioavailability [0, 2], they focus on general adult health or crop improvement [1, 6] and do not provide direct evidence on the specific growth outcomes in children relying on these proteins as primary staples.

How do specific cultural beliefs regarding 'insufficient milk' in rural South African communities mediate the relationship between maternal dietary diversity and the introduction of prelacteal feeds?

Why this gap exists: While the retrieved papers discuss general breastfeeding barriers in South Africa [8] and cultural influences in other regions like Ethiopia [6] and Malaysia [9], none specifically address the mediation of 'insufficient milk' beliefs on the relationship between maternal dietary diversity and prelacteal feeds in rural South African communities.

Sources

  1. African Political Systems.American Sociological Review, 1940
  2. Maternal nutrition counselling is associated with reduced stunting prevalence and improved feeding practices in early childhood: a post-program comparison studyNutrition Journal, 2019
  3. Trends and determinants of early initiation of breastfeeding and exclusive breastfeeding in Ethiopia from 2000 to 2016International Breastfeeding Journal, 2019
  4. Marketing of commercial milk formula: a system to capture parents, communities, science, and policyThe Lancet, 2023
  5. Facilitators, barriers, and factors determining the willingness to donate human milk among postpartum mothers in a tertiary women's hospital in Nepal: a cross-sectional study.International breastfeeding journal, 2026
  6. Assessment of Infant and Young Child Feeding Practices among Mothers Attending Maternal and Child Health Clinic at a Tertiary Hospital, North Karnataka, India - A Cross-sectional Study.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine, 2025
  7. Sociocultural and structural influences on infant and young child feeding in pastoralist communities of Afar, Ethiopia: a qualitative phenomenological study.BMJ open, 2026
  8. Knowledge, attitude, and practice of exclusive breastfeeding among mothers in East Africa: a systematic reviewInternational Breastfeeding Journal, 2020
  9. Facilitators and barriers associated with breastfeeding among mothers attending primary healthcare facilities in Mpumalanga, South Africa.Frontiers in nutrition, 2023
  10. Assessing the Influence of Cultural Beliefs and Practices on Early Breastfeeding Initiation Rates in Rural Sarawak Communities, MalaysiaScientific Journal of Pediatrics, 2023

To what extent do changes in the maternal microbiota (gut, oral, or vaginal) during pregnancy mediate the relationship between maternal perinatal anxiety/depression and the neurodevelopmental outcomes of the offspring?

Why this gap exists: While recent studies confirm associations between maternal mental health and microbiota composition (Abstract 5, 8) and suggest the microbiome-gut-brain axis influences neurodevelopment (Abstract 0, 2), the retrieved evidence does not contain studies that directly test the mediating role of maternal microbiota changes between perinatal anxiety/depression and offspring neurodevelopmental outcomes.

What is the comparative efficacy and cost-effectiveness of the one-step 75g OGTT versus the two-step (50g GCT followed by 100g OGTT) diagnostic approach in preventing adverse maternal and neonatal outcomes?

Why this gap exists: While Abstract [7] compares diagnostic criteria and Abstract [4] compares 75g and 100g OGTTs, the retrieved evidence lacks direct, comparative studies on the cost-effectiveness and relative efficacy of the one-step versus two-step *approaches* in preventing adverse outcomes, leaving the specific question unresolved.

Sources

  1. Glucose Intolerance after a Recent History of Gestational Diabetes Based on the 2013 WHO CriteriaPLoS ONE, 2016
  2. A Multicenter, Randomized Trial of Treatment for Mild Gestational DiabetesNew England Journal of Medicine, 2009
  3. Standards of Medical Care in Diabetes—2013Diabetes Care, 2012
  4. An Update on Screening Strategies for Gestational Diabetes Mellitus: A Narrative ReviewDiabetes Metabolic Syndrome and Obesity, 2021
  5. Comparison between 75-g and 100-g oral glucose tolerance tests using international association of diabetes and pregnancy study group one-step diagnostic threshold to detect gestational diabetes mellitusFrontiers in Endocrinology, 2025
  6. Large language models for generating longitudinal synthetic data in low-risk pregnancy care.Data in brief, 2026
  7. Effects of physical activity and diet in pregnancy to prevent gestational diabetes: an individual participant data (IPD) meta-analysis on the differential effects of interventions with economic evaluation.Health technology assessment (Winchester, England), 2026
  8. 187-OR: Randomized Clinical Trial of the IADPSG vs. Carpenter Coustan Criteria for Diagnosis of Gestational Diabetes MellitusDiabetes, 2020
  9. Prevalence of gestational diabetes mellitus and results of the screening tests at a tertiary referral center: A cross-sectional study.Diabetes & metabolic syndrome, 2019
  10. Gestational Diabetes in Somali Women: Neglected Risks for Maternal and Neonatal Health.International journal of women's health, 2026

What are the comparative efficacy and adherence rates of new short-course latent tuberculosis infection (LTBI) regimens versus traditional long-course therapies in high-burden, low-resource settings?

Why this gap exists: While a 2023 network meta-analysis [6] synthesizes general efficacy and adherence data for LTBI regimens, the retrieved evidence lacks direct comparative studies specifically focused on high-burden, low-resource settings, leaving the specific constraints of these environments unresolved.

How does the aggressive marketing of breastmilk substitutes in low-income countries specifically modify the effectiveness of workplace breastfeeding interventions on exclusive breastfeeding rates?

Why this gap exists: While the retrieved literature addresses workplace barriers [7] and the negative impact of breastmilk substitute marketing [2, 9] separately, no study directly investigates the interaction effect or modification of workplace intervention effectiveness by aggressive marketing in low-income countries.

Publications

Anti-black pod disease activity of leaf extract of Carica papaya Linn

Journal of Natural Pesticide Research · 2024 · 1 citations

Toxicity and therapeutic applications of citrus essential oils (CEOs): a review

International Journal of Food Properties · 2023 · 54 citations

Antidepressant and Anxiolytic Effects and Subacute Toxicity of the Aerial Parts of Psychotria ankasensis J.B.Hall (Rubiaceae) in Murine Models

Evidence-based Complementary and Alternative Medicine · 2021 · corresponding author · 7 citations

Indigenous Knowledge Affords Antimicrobial Plants for the Management of Infections

International Journal of TROPICAL DISEASE & Health · 2021 · 3 citations

Indigenous Medicinal Plants as Biofilm Inhibitors for the Mitigation of Antimicrobial Resistance

Advances in Pharmacological and Pharmaceutical Sciences · 2020 · 10 citations

CCDC 1909815: Experimental Crystal Structure Determination

The Cambridge Structural Database · 2020

Development and validation of a radical scavenging antioxidant assay using potassium permanganate

Journal of Scientific and Innovative Research · 2016 · 10 citations

Pharmacognostic and physico-chemical investigation of Palisota hirsuta (K. Schum) (Commelinaceae)

Journal of natural product and plant resources · 2016 · 3 citations

Antinociceptive Ecdysteroids and Other Constituents of Palisota hirsuta K. Schum (Commelinaceae)

Journal of Applied Pharmaceutical Science · 2016 · 2 citations

CCDC 1051612: Experimental Crystal Structure Determination

The Cambridge Structural Database · 2016