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What is the comparative efficacy of digital or telehealth lactation support versus traditional face-to-face peer support on breastfeeding exclusivity rates during pandemic-related social restrictions?
Why this gap exists: While Abstract [3] confirms the general effectiveness of digital health interventions on breastfeeding practices and Abstract [0] notes the cancellation of face-to-face peer support during the pandemic, the retrieved evidence does not contain a direct comparative study between digital/telehealth lactation support and traditional face-to-face peer support specifically regarding exclusivity rates during social restrictions.
How does the longitudinal trajectory of maternal stress and resilience during pregnancy specifically mediate the association between social determinants of health (e.g., socioeconomic status, structural inequality) and infant cognitive or emotional development outcomes?
Why this gap exists: While the retrieved literature confirms associations between socioeconomic disadvantage, maternal stress, and infant neurodevelopment, it does not resolve the specific question of how longitudinal trajectories of maternal stress and resilience mediate these associations, as the studies focus on broad correlations or static measures rather than dynamic mediation pathways.
Chronic stress may disrupt covariant fluctuations of vitamin D and cortisol plasma levels in pregnant sheep during the last trimester: a preliminary report — arXiv preprint, 2019
What is the comparative efficacy of digital versus in-person delivery of mental health interventions for mitigating the increased risk of perinatal depression and anxiety in low-income and middle-income countries during future pandemic-like disruptions?
Why this gap exists: While abstracts [6] and [8] compare digital and in-person delivery during the pandemic, they are set in high-income contexts (Spain, unspecified high-income), and abstract [7] focuses on LMICs but lacks a comparative digital vs. in-person design, leaving the specific question of comparative efficacy in LMICs unresolved.
Detecting anxiety and depression in dialogues: a multi-label and explainable approach — de Arriba-Pérez, F., García-Méndez, S. (2024). Detecting anxiety and depression in dialogues: a multi-label and explainable approach. In Proceedings of the 3rd AIxIA Workshop on Artificial Intelligence For Healthcare (pp. 257-271), 2024
Detecting anxiety and depression in dialogues: a multi-label and explainable approach — de Arriba-Pérez, F., García-Méndez, S. (2024). Detecting anxiety and depression in dialogues: a multi-label and explainable approach. In Proceedings of the 3rd AIxIA Workshop on Artificial Intelligence For Healthcare (pp. 257-271), 2024
What are the comparative efficacy and adherence rates of new short-course latent tuberculosis infection (LTBI) regimens versus traditional long-course therapies in high-burden, low-resource settings?
Why this gap exists: While a 2023 network meta-analysis [6] synthesizes general efficacy and adherence data for LTBI regimens, the retrieved evidence lacks direct comparative studies specifically focused on high-burden, low-resource settings, leaving the specific constraints of these environments unresolved.
How do specific policy frameworks regarding social protection and food systems in low-income countries moderate the projected increase in child wasting and maternal undernutrition caused by economic shocks like the COVID-19 pandemic?
Why this gap exists: While the retrieved literature confirms the projected increase in child wasting and maternal undernutrition due to COVID-19 disruptions [0] and explores general concepts of food system resilience [2] and social protection [3], no study directly quantifies how specific policy frameworks moderate these projected outcomes, leaving the core interaction unresolved.
How does the aggressive marketing of breastmilk substitutes in low-income countries specifically modify the effectiveness of workplace breastfeeding interventions on exclusive breastfeeding rates?
Why this gap exists: While the retrieved literature addresses workplace barriers [7] and the negative impact of breastmilk substitute marketing [2, 9] separately, no study directly investigates the interaction effect or modification of workplace intervention effectiveness by aggressive marketing in low-income countries.