Kwadwo Koram

University of Ghana

282 publications · 9,386 citations · ORCID 0000-0003-4274-6516

Malaria Research and ControlMosquito-borne diseases and controlParasites and Host InteractionsGlobal Maternal and Child HealthTuberculosis Research and Epidemiology

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Kwadwo Koram is a public health researcher specializing in infectious disease epidemiology, with a primary focus on malaria control, drug resistance surveillance, and vaccine evaluation in Ghana. Koram's work encompasses clinical trials for antimalarial therapies, molecular surveillance of parasite populations, and health systems research regarding non-communicable diseases and pandemic response. Recent contributions include investigations into Lassa fever vaccine safety, malaria parasite genetics, and the impact of COVID-19 on health services.

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What are the comparative efficacy and adherence rates of new short-course latent tuberculosis infection (LTBI) regimens versus traditional long-course therapies in high-burden, low-resource settings?

Why this gap exists: While a 2023 network meta-analysis [6] synthesizes general efficacy and adherence data for LTBI regimens, the retrieved evidence lacks direct comparative studies specifically focused on high-burden, low-resource settings, leaving the specific constraints of these environments unresolved.

Sources

New developments in tuberculosis diagnosis and treatment — Breathe, 2022
Latent Tuberculosis and HIV Infection — Current Infectious Disease Reports, 2020
Epidemic and pandemic viral infections: impact on tuberculosis and the lung — European Respiratory Journal, 2020
Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems — Nature Reviews Drug Discovery, 2023
Drug resistant tuberculosis: Implications for transmission, diagnosis, and disease management — Frontiers in Cellular and Infection Microbiology, 2022
Updates on the Treatment of Drug-Susceptible and Drug-Resistant Tuberculosis: An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline — American Journal of Respiratory and Critical Care Medicine, 2024
Efficacy and safety of different regimens in the treatment of patients with latent tuberculosis infection: a systematic review and network meta-analysis of randomized controlled trials — Archives of Public Health, 2023
Improving Tuberculosis Medication Adherence: The Potential of Integrating Digital Technology and Health Belief Model — Tuberculosis & respiratory diseases, 2023
Mind the gap – Managing tuberculosis across the disease spectrum — EBioMedicine, 2022
Tuberculosis Preventive Treatment in High TB-Burden Settings: A State-of-the-Art Review — Drugs, 2024

How does the longitudinal trajectory of maternal stress and resilience during pregnancy specifically mediate the association between social determinants of health (e.g., socioeconomic status, structural inequality) and infant cognitive or emotional development outcomes?

Why this gap exists: While the retrieved literature confirms associations between socioeconomic disadvantage, maternal stress, and infant neurodevelopment, it does not resolve the specific question of how longitudinal trajectories of maternal stress and resilience mediate these associations, as the studies focus on broad correlations or static measures rather than dynamic mediation pathways.

Sources

Maternal Depression During Pregnancy and the Postnatal Period — JAMA Psychiatry, 2013
Socioeconomic disadvantage, gestational immune activity, and neurodevelopment in early childhood — Proceedings of the National Academy of Sciences, 2017
Disrupted beginnings: Neurodevelopmental outcomes of COVID-19 lockdowns in early childhood (Review). — Experimental and therapeutic medicine, 2026
Pregnancy as a period of risk, adaptation, and resilience for mothers and infants — Development and Psychopathology, 2020
The influence of attachment and relational quality on developmental outcomes across the lifespan: a systematic review and meta-analytic insights (2014-2024). — Frontiers in psychology, 2026
Nutrition as the Foundation of Human Capital: Pathways to Holistic Development. — Maternal & child nutrition, 2026
Chronic stress may disrupt covariant fluctuations of vitamin D and cortisol plasma levels in pregnant sheep during the last trimester: a preliminary report — arXiv preprint, 2019
Resilience and Stress during Pregnancy: A Comprehensive Multidimensional Approach in Maternal and Perinatal Health — The Scientific World JOURNAL, 2021
Maternal Stress During Pregnancy and Infant and Child Outcome — Oxford Handbooks Online, 2014
Maternal Docosahexaenoic Acid Status During Pregnancy and Its Impact on Infant Neurodevelopment — 2020

What is the comparative effectiveness of telemedicine versus traditional in-person care in maintaining essential antenatal coverage and reducing maternal mortality in low-income and middle-income countries during future health system shocks?

Why this gap exists: While abstracts [4], [7], [8], and [9] discuss digital tools and maternity care in low- and middle-income countries, none provide a direct comparative effectiveness analysis of telemedicine versus in-person care regarding maternal mortality during health system shocks, leaving the specific question unresolved.

Sources

COVID-19 and resilience of healthcare systems in ten countries — Nature Medicine, 2022
Community Health Workers Can Provide Psychosocial Support to the People During COVID-19 and Beyond in Low- and Middle- Income Countries — Frontiers in Public Health, 2021
Social Impacts and Responses Related to COVID-19 in Low- and Middle-income Countries — OpenDocs (Institute of Development Studies), 2020
Seizing the moment to rethink health systems — The Lancet Global Health, 2021
Use of mHealth in promoting maternal and child health in “BIMARU” states of India “A health system strengthening strategy”: Systematic literature review — PLOS Digital Health, 2024
Investments for effective functionality of health systems towards Universal Health Coverage in Africa: A scoping review — PLOS Global Public Health, 2022
Infant and young child feeding — OECD eBooks, 2023
Facilitators and barriers to the implementation of a Mobile Health Wallet for pregnancy-related health care: A qualitative study of stakeholders’ perceptions in Madagascar — PLoS ONE, 2020
The impact of digital interventions on health insurance coverage for reproductive, maternal, newborn and child health services utilization in Kakamega, Kenya: a cluster randomized controlled trial — Health Policy and Planning, 2024
Seeking digital maternity healthcare during the pandemic health system shock: a systematic review of women's experiences in low- and middle-income countries — Frontiers in Reproductive Health, 2026

How do specific policy interventions aimed at improving female education and labor force participation accelerate the 'maternal mortality transition' in regions currently experiencing high maternal mortality?

Why this gap exists: While the retrieved literature establishes links between female education, political power, and health outcomes (e.g., [3], [6], [9]), no study directly addresses how specific labor or education policy interventions accelerate the 'maternal mortality transition' in high-mortality regions, leaving the mechanism and impact of such specific policies unresolved.

Sources

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 — The Lancet, 2024
Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 — The Lancet, 2024
Determinants of female labor force participation: implications for policy in Qatar — Cogent Social Sciences, 2022
Maternal Mortality and Women’s Political Power — Journal of the European Economic Association, 2023
The labor force participation of Indian women before and after widowhood — Demographic Research, 2020
The public health effects of interventions similar to basic income: a scoping review — The Lancet Public Health, 2020
Differential impact of maternal education on under-five mortality in rural and urban India — Health & Place, 2023
Public Health Expenditure and Under-five Mortality in Nigeria: An Overview for Policy Intervention — Open Access Macedonian Journal of Medical Sciences, 2020
Efficacy of companion-integrated childbirth preparation for childbirth fear, self-efficacy, and maternal support in primigravid women in Malawi — BMC Pregnancy and Childbirth, 2020
The contribution of female health to economic development — The Economic Journal, 2020

How does the consumption of plant-based proteins, specifically those high in anti-nutritional factors like phytates and trypsin inhibitors, affect mineral bioavailability and growth outcomes in children relying on these proteins as primary staples?

Why this gap exists: While the retrieved papers confirm that anti-nutritional factors like phytates and trypsin inhibitors reduce mineral bioavailability [0, 2], they focus on general adult health or crop improvement [1, 6] and do not provide direct evidence on the specific growth outcomes in children relying on these proteins as primary staples.

Sources

Plant food anti-nutritional factors and their reduction strategies: an overview — Food Production Processing and Nutrition, 2020
Sustaining Protein Nutrition Through Plant-Based Foods — Frontiers in Nutrition, 2022
Is There Such a Thing as “Anti-Nutrients”? A Narrative Review of Perceived Problematic Plant Compounds — Nutrients, 2020
Faba Bean: An Untapped Source of Quality Plant Proteins and Bioactives — Nutrients, 2022
Nutritional properties and health aspects of pulses and their use in plant‐based yogurt alternatives — Comprehensive Reviews in Food Science and Food Safety, 2021
Grains – a major source of sustainable protein for health — Nutrition Reviews, 2021
Healthy and Resilient Cereals and Pseudo-Cereals for Marginal Agriculture: Molecular Advances for Improving Nutrient Bioavailability — Frontiers in Genetics, 2020
Protein Quality in Perspective: A Review of Protein Quality Metrics and Their Applications — Nutrients, 2022
Health Benefits of Plant-Based Nutrition: Focus on Beans in Cardiometabolic Diseases — Nutrients, 2021
Bioavailability of Micronutrients From Nutrient-Dense Whole Foods: Zooming in on Dairy, Vegetables, and Fruits — Frontiers in Nutrition, 2020

Publications

Efficacy of artemether-lumefantrine combination for the treatment of uncomplicated Plasmodium falciparum malaria after 16 years of its introduction into Ghana’s antimalarial medicines policy

Malaria Journal · 2026

Therapeutic efficacy of dihydroartemisinin-piperaquine and artesunate-pyronaridine combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Ghana, 2023

Frontiers in Public Health · 2026

Evaluation of SARS-CoV-2 Seroprevalence and Variant Distribution During the Delta–Omicron Transmission Waves in Greater Accra, Ghana, 2021

Viruses · 2025 · 3 citations

Investigating Environmental Determinants of Hookworm Transmission using GPS Tracking and Metagenomics Technologies

American Journal of Tropical Medicine and Hygiene · 2025 · 3 citations

Safety, tolerability, and immunogenicity of INO-4500, a synthetic DNA-based vaccine against Lassa virus, in a phase 1b clinical trial in healthy Ghanaian adults

Frontiers in Immunology · 2025 · 1 citations

The cascade of hypertension prevalence, awareness, treatment, and control in urban-poor communities in Accra, Ghana: a population-based household survey

BMC Public Health · 2025 · 1 citations

Barriers and facilitators of integrating cervical cancer screening into routine HIV care and acceptability of self-sampling for HPV DNA testing among people with HIV: an exploratory study in southern Ghana

Frontiers in Public Health · 2025 · 1 citations

Performance of eight serum cytokine/chemokine biomarkers in discriminating between active and latent tuberculosis infection in Ghana

Frontiers in Immunology · 2025 · 1 citations

Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

eLife · 2025 · 1 citations

No evidence of MMR induced trained immunity to prevent SARS COV2: results from a multi-centre RCT

Frontiers in Immunology · 2025 · 1 citations

Author response: Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

2025

Additional file 1 of The cascade of hypertension prevalence, awareness, treatment, and control in urban-poor communities in Accra, Ghana: a population-based household survey

Figshare · 2025

Author response: Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

2025

Additional file 1 of The cascade of hypertension prevalence, awareness, treatment, and control in urban-poor communities in Accra, Ghana: a population-based household survey

Open MIND · 2025

Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

eLife · 2025

Longitudinal analysis of the prevalence of minor Plasmodium spp. in the reservoir of asymptomatic infections through sequential interventions in Northern Sahelian Ghana

medRxiv · 2025

Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi

The Lancet · 2024 · 84 citations

The contextual awareness, response and evaluation (CARE) diabetes project: study design for a quantitative survey of diabetes prevalence and non-communicable disease risk in Ga Mashie, Accra, Ghana

Global Health Action · 2024 · 16 citations

Household economic burden of type-2 diabetes and hypertension comorbidity care in urban-poor Ghana: a mixed methods study

BMC Health Services Research · 2024 · 16 citations

Implementation of national policies and interventions (WHO Best Buys) for non-communicable disease prevention and control in Ghana: a mixed methods analysis

Health Research Policy and Systems · 2024 · 11 citations

Prevalence of diabetes and associated risk factors in Ga Mashie, Accra, Ghana – the CARE Diabetes community-based survey

medRxiv · 2024 · 7 citations

Putative molecular markers of Plasmodium falciparum resistance to antimalarial drugs in malaria parasites from Ghana

Frontiers in Epidemiology · 2024 · 6 citations

Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

eLife · 2024 · 1 citations

Author response: Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

2024

Implementation of national policies and interventions (WHO Best Buys) for non-communicable disease prevention and control in Ghana: a mixed methods analysis

Research Square · 2024

Injury and violence in the context of sustainable development01. Optimizing of uptake of 3 WHO injury surveillance guidelines through digitization02. Prospective study of pediatric neurotrauma surgery in Addis Ababa, Ethiopia: clinical presentation, injury types, and trauma causes03. Injury Surveillance Tanzania — a 10-year experience04. Characteristics of traumatic injury requiring surgical care in Ethiopia05. Surgical, obstetric, trauma, and anesthesia-related health policies in Ghana: analysis and opportunities06. Trauma: a significant risk of catastrophic expenditure in Hawassa, Ethiopia07. Improvements in trauma care and outcome using a trauma intake form with built-in decision support prompts at non-tertiary hospitals in Ghana: a randomized clinical trial08. Burden of injury in Africa, 2010–2021: analysis of Global Burden of Disease 202109. A non-lethal left-sided thoracic impalement injury10. Withdrawn11. Pediatric falls: an analysis of patterns of injury and associated mortality from falls in urban India12. Injuries to the maxillofacial region from improvised explosive devices: diagnostic findings and treatment approaches in a resource-limited setting13. Adult surgical admissions at a Botswana tertiary teaching hospital — spectrum, comorbidity profile, and outcomes14. Exploring police officers’ perspectives on road traffic accident dynamics, management, and prevention in Jimma, Ethiopia: a phenomenological qualitative study15. Effectiveness of steam sterilization practice on reusable surgical instruments and factors associated with ineffective sterilization in selected public hospitals16. Soft-tissue reconstruction of type IIIB open tibial fractures in low- and middle-income countries: a literature review17. What are the core competencies for global surgical training? A scoping review18. Delays in care for children with low anorectal malformations in southwestern Uganda: a cross-sectional survey19. Prehospital care for trauma patients in Ethiopia: a systematic review20. Improving access to pediatric foot and ankle surgery in low-resource areas using smart glasses technology for telementoring of surgeons — a pilot study21. Pathways to equitable clinical exchanges: a review of licensure requirements of 52 medical boards in the United States22. Effectiveness of a hybrid trauma training course for health care providers in Kenya23. Incisional negative-pressure wound therapy as breakthrough adjunct in preventing surgical site infection in contaminated and dirty laparotomy wounds in sub-Saharan African children24. Comparing clinical with microbiological assessment in predicting skin graft take at National Hospital, Abuja25. Etiology and patterns of pediatric long bone fractures seen at a regional referral and university teaching hospital in southwestern Uganda26. Late-presenting developmental dysplasia of the hip in Ethiopia: a retrospective cohort study of 116 hips27. Addressing critical challenges: aortoiliac occlusive disease management in Ethiopia28. Patient-centred surgical care for children in low- and middle-income countries — a systematic scoping review of the literature29. Virtual and augmented reality for simulation training in low- and middle-income countries — a systematic review30. Clinical profile and outcome of penetrating traumatic brain injury war victim military patients in Ethiopia: a prospective study31. Addressing the paramedic shortage in Ethiopia: a critical analysis for emergency medical service improvement32. Empowering voices: the role of social media in civilian agency during the Sudanese Civil War33. Assessment of knowledge, attitude, and practice of Basic Life Support (BLS) among medical interns of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia34. Snapshot of trauma and anesthesia care capacity and preparedness in resource-limited setup in the face of war: the case of northern Ethiopia35. Prehospital features of trauma victims and their association with outcomes in southern Ethiopia36. Assessing prioritization of trauma and surgical care in Uganda’s health policy documents: a bibliometric analysis37. Readiness of tertiary care hospitals in Ethiopia for trauma registry implementation38. Rapid review: humanitarian organizations and existing policy on sustainable surgical care in conflict and post-conflict zones39. The United Nations Global Surgery Learning Hub: enhancing human resource capacity in surgical care40. Disaster surge capacity rise through reverse triage in Addis Ababa hospitals41. Outcome of major burn injury management involving high-dose multivitamins in Enugu, Nigeria42. A collaboration between Hawassa and Houston in a competitive hackathon for surgical innovation43. Humanitarian surgery: an experience from the Afar region of Ethiopia

Canadian Journal of Surgery · 2024

Comparison of molecular surveillance methods to assess changes in the population genetics of Plasmodium falciparum in high transmission

Frontiers in Parasitology · 2023 · 29 citations

Health system adaptions to improve care for people living with non-communicable diseases during COVID-19 in low-middle income countries: A scoping review

Journal of Global Health · 2023 · 18 citations

Performance of SNP barcodes to determine genetic diversity and population structure of Plasmodium falciparum in Africa

Frontiers in Genetics · 2023 · 14 citations

Therapeutic efficacy of dihydroartemisinin-piperaquine combination for the treatment of uncomplicated malaria in Ghana

Frontiers in Cellular and Infection Microbiology · 2023 · 13 citations

Modeling SARS-CoV-2 antibody seroprevalence and its determinants in Ghana: A nationally representative cross-sectional survey

PLOS Global Public Health · 2023 · 13 citations

Coinfection of Malaria and Bacterial Pathogens among Acute Febrile Patients in Selected Clinics in Ghana

American Journal of Tropical Medicine and Hygiene · 2023 · 9 citations

Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

2023 · 8 citations

Health system adaptions to improve care for people living with non-communicable diseases during COVID-19 in low-middle income countries: A scoping review

Journal of Global Health · 2023 · 4 citations

Antimicrobial use of patients with sexually transmitted infection symptoms prior to presentation at five health facilities in Southern Ghana

Antimicrobial Resistance and Infection Control · 2023 · 4 citations

Investigating Environmental Determinants of Soil-Transmitted Helminths Transmission using GPS Tracking and Metagenomics Technologies

medRxiv · 2023 · 4 citations

Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

medRxiv · 2023 · 3 citations

Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

eLife · 2023 · 2 citations

Regular deworming and seasonality are potential challenges but also offer opportunities for hookworm elimination

medRxiv · 2023 · 1 citations

Author Response: Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

2023 · 1 citations

Reviewer #2 (Public Review): Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

2023

Reviewer #3 (Public Review): Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

2023

Reviewer #1 (Public Review): Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

2023

Antimicrobial use of patients with sexually transmitted infection symptoms prior to presentation at five health facilities in Southern Ghana

Research Square · 2023

PA-224 Impact of diabetes mellitus on tuberculosis treatment outcome

2023

Age-specific patterns of DBLα var diversity can explain why residents of high malaria transmission areas remain susceptible to Plasmodium falciparum blood stage infection throughout life

International Journal for Parasitology · 2022 · 38 citations

Indoor residual spraying with a non-pyrethroid insecticide reduces the reservoir of Plasmodium falciparum in a high-transmission area in northern Ghana

PLOS Global Public Health · 2022 · corresponding author · 36 citations

Diarrhea-Causing Bacteria and Their Antibiotic Resistance Patterns Among Diarrhea Patients From Ghana

Frontiers in Microbiology · 2022 · 30 citations

Assessment of oral health status in a Ghanaian population: rationale, methods, and population characteristics

BMC Oral Health · 2022 · 24 citations

Novel pfk13 polymorphisms in Plasmodium falciparum population in Ghana

Scientific Reports · 2022 · 20 citations

Haematological consequences of acute uncomplicated falciparum malaria: a WorldWide Antimalarial Resistance Network pooled analysis of individual patient data

BMC Medicine · 2022 · 15 citations

Strengthening surveillance in Ghana against public health emergencies of international concern

Tropical Medicine and Health · 2022 · 8 citations

Cervical cancer prevention in Ghana

Ghana Medical Journal · 2022 · corresponding author · 7 citations

Copy number variation of plasmepsins 2 and 3 genes in Plasmodium falciparum isolates and implication for dihydroartemisinin-piperaquine resistance in Ghana

Health Sciences Investigations Journal · 2022 · 1 citations

Determination of SARS-CoV-2 Variants and Seroprevalence in Accra, Ghana during the Delta-Omicron Waves

Preprints.org · 2022 · 1 citations

Correction to: Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools

Malaria Journal · 2022 · 1 citations

Effect of antipyretics on performance of influenza surveillance in Ghana

Influenza and Other Respiratory Viruses · 2022

Modeling SARS-CoV-2 Antibody Seroprevalence and its Determinants in Ghana: A Nationwide Cross-Sectional Survey

SSRN Electronic Journal · 2022

Gut microbiota signature of pathogen-dependent dysbiosis in viral gastroenteritis

Scientific Reports · 2021 · 48 citations

Trends and predictive factors for treatment failure following artemisinin-based combination therapy among children with uncomplicated malaria in Ghana: 2005–2018

BMC Infectious Diseases · 2021 · 18 citations

Species composition and risk of transmission of some Aedes-borne arboviruses in some sites in Northern Ghana

PLoS ONE · 2021 · 18 citations

Guiding placement of health facilities using multiple malaria criteria and an interactive tool

Malaria Journal · 2021 · 17 citations

High frequency of the Duffy-negative genotype and absence of Plasmodium vivax infections in Ghana

Malaria Journal · 2021 · 15 citations

The impact of indoor residual spraying on Plasmodium falciparum microsatellite variation in an area of high seasonal malaria transmission in Ghana, West Africa

Molecular Ecology · 2021 · 9 citations

Genomic epidemiological analysis identifies high relapse among individuals with recurring tuberculosis and provides evidence of recent household-related transmission of tuberculosis in Ghana

International Journal of Infectious Diseases · 2021 · 7 citations

Ex vivo Sensitivity Profile of Plasmodium falciparum Clinical Isolates to a Panel of Antimalarial Drugs in Ghana 13 Years After National Policy Change

Infection and Drug Resistance · 2021 · 7 citations

COVID-19, chronic conditions and structural poverty: A social psychological assessment of the needs of a marginalized community in Accra, Ghana

Journal of Social and Political Psychology · 2021 · 4 citations

Data management during COVID-19 outbreak response in Ghana: a reference laboratory perspective on key issues and measures

Ghana Medical Journal · 2021 · 3 citations

SARS CoV2 Seroprevalence in Rural and Urban Populations In Ghana

Zenodo (CERN European Organization for Nuclear Research) · 2021 · 2 citations

Incidence of Laboratory-Confirmed Influenza among HIV-Infected versus HIV-Uninfected Individuals in Two Districts of Ghana, 2014 to 2016

American Journal of Tropical Medicine and Hygiene · 2021 · 2 citations

Guiding placement of health facilities using malaria criteria and interactive tool

Research Square · 2021 · 1 citations

Utility of early diagnosis, contact tracing and stakeholder engagement in outbreak response in three COVID-19 outbreak settings in Ghana

Ghana Medical Journal · 2021 · 1 citations

SARS CoV2 Seroprevalence in Rural and Urban Populations In Ghana

Zenodo (CERN European Organization for Nuclear Research) · 2021

Effect of In-service training intervention and SMS messages on Malaria case management

Figshare · 2021

Oral Health Status Assessment of an African Population: Rationale, Methods and Population Characteristics

Research Square · 2021

Systematic review of prediction models for gestational hypertension and preeclampsia

PLoS ONE · 2020 · 92 citations

Responding to the COVID-19 pandemic in Ghana

Ghana Medical Journal · 2020 · 91 citations

Safety, reactogenicity, and immunogenicity of a chimpanzee adenovirus vectored Ebola vaccine in adults in Africa: a randomised, observer-blind, placebo-controlled, phase 2 trial

The Lancet Infectious Diseases · 2020 · 76 citations

Safety, reactogenicity, and immunogenicity of a chimpanzee adenovirus vectored Ebola vaccine in children in Africa: a randomised, observer-blind, placebo-controlled, phase 2 trial

The Lancet Infectious Diseases · 2020 · 64 citations

Epidemiology of COVID-19 outbreak in Ghana, 2020

Ghana Medical Journal · 2020 · 59 citations

Building cardiovascular disease competence in an urban poor Ghanaian community: A social psychology of participation approach

Journal of Community & Applied Social Psychology · 2020 · 31 citations

Whole Genome Sequencing and Spatial Analysis Identifies Recent Tuberculosis Transmission Hotspots in Ghana

Frontiers in Medicine · 2020 · 27 citations

Coverage of intermittent preventive treatment of malaria in pregnancy (IPTp) influences delivery outcomes among women with obstetric referrals at the district level in Ghana

Malaria Journal · 2020 · 23 citations

Impact of an Irrigation Dam on the Transmission and Diversity of Plasmodium falciparum in a Seasonal Malaria Transmission Area of Northern Ghana

Journal of Tropical Medicine · 2020 · 20 citations

Evolution of Antimalarial Drug Resistance Markers in the Reservoir of Plasmodium falciparum Infections in the Upper East Region of Ghana

The Journal of Infectious Diseases · 2020 · 20 citations

Antibiotic prescription for febrile outpatients: a health facility-based secondary data analysis for the Greater Accra region of Ghana

BMC Health Services Research · 2020 · 17 citations

Assessment of antimalarial drug resistant markers in asymptomatic Plasmodium falciparum infections after 4 years of indoor residual spraying in Northern Ghana

PLoS ONE · 2020 · 13 citations

Plasmodium falciparum genetic factors rather than host factors are likely to drive resistance to ACT in Ghana

Malaria Journal · 2020 · 9 citations

Ghana and the COVID-19 pandemic

Ghana Medical Journal · 2020 · 5 citations

Perspectives on Research Internships for Medical Students and Young Doctors in Ghana: An Opportunity to Replenish the Stock of Physician Investigators?

Advances in Medical Education and Practice · 2020 · 2 citations

High frequency of the Duffy-negative genotype and absence of Plasmodium vivax infections in Ghana

Research Square · 2020 · 2 citations

Human coronaviruses in persons with acute respiratory infections in Ghana

Health Sciences Investigations Journal · 2020 · 1 citations

Plasmodium falciparum genetic factors rather than host factors are likely to drive resistance to ACT in Ghana

Research Square · 2020 · 1 citations

Species composition and risk of transmission of Aedes -borne arboviruses around some Yellow hotspot areas in Northern Ghana

bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations

Antibiotics Prescription for Febrile Outpatients: A Health Facility-Based Secondary Data Analysis for the Greater Accra region of Ghana

Research Square · 2020

Antibiotics prescription for febrile outpatients: a health facility-based secondary data analysis for the Greater Accra region of Ghana

Research Square · 2020

Antibiotic prescription for febrile outpatients: a health facility-based secondary data analysis for the Greater Accra region of Ghana

Research Square · 2020

Drug sensitivity of Plasmodium falciparum field isolates to selected antimalarial drugs in Ghana using the in-vitro DAPI assay

2020

Plasmodium Falciparum Genetic Factors Rather Than The Hosts' Are Likely To Drive Resistance To Acts In Ghana

Research Square · 2020

Plasmodium falciparum genetic factors rather than the hosts' are likely to drive resistance to ACTs in Ghana

Research Square · 2020

Plasmodium falciparum genetic factors rather than the hosts' are likely to drive resistance to acts in ghana.

Research Square · 2020

The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density

Nature Communications · 2019 · 226 citations

Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania

Nature Communications · 2019 · 221 citations

Probing the composition of Plasmodium species contained in malaria infections in the Eastern region of Ghana

BMC Public Health · 2019 · 72 citations

Therapeutic efficacy of artesunate–amodiaquine and artemether–lumefantrine combinations for uncomplicated malaria in 10 sentinel sites across Ghana: 2015–2017

Malaria Journal · 2019 · 49 citations

Plasmodium falciparum Kelch Propeller Polymorphisms in Clinical Isolates from Ghana from 2007 to 2016

Antimicrobial Agents and Chemotherapy · 2019 · 43 citations

Extent of inappropriate prescription of artemisinin and anti-malarial injections to febrile outpatients, a cross-sectional analytic survey in the Greater Accra region, Ghana

Malaria Journal · 2019 · 42 citations

Characterizing local-scale heterogeneity of malaria risk: a case study in Bunkpurugu-Yunyoo district in northern Ghana

Malaria Journal · 2019 · 40 citations

Prevalence of asymptomatic malaria parasitaemia following mass testing and treatment in Pakro sub-district of Ghana

BMC Public Health · 2019 · 40 citations

Prevalence and correlates of stroke among older adults in Ghana: Evidence from the Study on Global AGEing and adult health (SAGE)

PLoS ONE · 2019 · 35 citations

Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum Erythrocyte Membrane Protein 1 Antigen Family Varies between Groups A, B, and C

Infection and Immunity · 2019 · 31 citations

TB-diabetes co-morbidity in Ghana: The importance of Mycobacterium africanum infection

PLoS ONE · 2019 · corresponding author · 26 citations

Immune Signature Against Plasmodium falciparum Antigens Predicts Clinical Immunity in Distinct Malaria Endemic Communities

Molecular & Cellular Proteomics · 2019 · 24 citations

Challenges and perceptions of implementing mass testing, treatment and tracking in malaria control: a qualitative study in Pakro sub-district of Ghana

BMC Public Health · 2019 · 21 citations

Explanatory models of stroke in Ghana: perspectives of stroke survivors and their caregivers

Ethnicity and Health · 2019 · 18 citations

Author Correction: The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density

Nature Communications · 2019 · 12 citations

Malaria vaccine deployment in Africa: focus on Ghana

Ghana Medical Journal · 2019 · 11 citations

Antigenicity and immune correlate assessment of seven Plasmodium falciparum antigens in a longitudinal infant cohort from northern Ghana

Scientific Reports · 2019 · 4 citations

Prevalence of asymptomatic malaria parasitaemia following mass testing and treatment in Pakro sub-district of Ghana

Research Square · 2019 · 3 citations

Re: Musings on malaria morbidity and mortality after the new Mosquirix® vaccine

Ghana Medical Journal · 2019 · 1 citations

Antibiotics prescription for febrile patients: associated factors in a health facility-based survey in the Greater Accra region of Ghana

Research Square · 2019 · 1 citations

Multicollinearity tests.

INDIGO (University of Illinois at Chicago) · 2019

Prevalence of asymptomatic malaria parasitaemia following mass testing and treatment in Pakro sub-district of Ghana

Research Square · 2019

Predictors of antibiotics prescription for febrile patients: A health facility-based survey in the Greater Accra region of Ghana

Research Square · 2019

Prevalence of asymptomatic malaria parasitaemia following mass testing and treatment in Pakro sub-district of Ghana

Research Square · 2019

Prevalence of asymptomatic malaria parasitaemia following mass testing and treatment in Pakro sub-district of Ghana

Research Square · 2019

In vitro antiprotozoan activity and mechanisms of action of selected <scp>G</scp>hanaian medicinal plants against Trypanosoma, Leishmania, and Plasmodium parasites

Phytotherapy Research · 2018 · 62 citations

Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates

Parasites & Vectors · 2018 · 43 citations

Reduced transmission of Mycobacterium africanum compared to Mycobacterium tuberculosis in urban West Africa

International Journal of Infectious Diseases · 2018 · 42 citations

Impact of indoor residual spraying on malaria parasitaemia in the Bunkpurugu-Yunyoo District in northern Ghana

Parasites & Vectors · 2018 · 39 citations

Detecting local risk factors for residual malaria in northern Ghana using Bayesian model averaging

Malaria Journal · 2018 · 35 citations

Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools

Malaria Journal · 2018 · 18 citations

Signatures of competition and strain structure within the major blood‐stage antigen of Plasmodium falciparum in a local community in Ghana

Ecology and Evolution · 2018 · 15 citations

Improved prediction of gestational hypertension by inclusion of placental growth factor and pregnancy associated plasma protein-a in a sample of Ghanaian women

Reproductive Health · 2018 · 10 citations

165. Improved prediction of gestational hypertension by inclusion of placental growth factor and Pregnancy Associated Plasma Protein-A in a sample of Ghanaian women

Pregnancy Hypertension · 2018

Additional file 1: of Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates

Figshare · 2018

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia

eLife · 2017 · 96 citations

Seasonal Variation in the Epidemiology of Asymptomatic Plasmodium falciparum Infections across Two Catchment Areas in Bongo District, Ghana

American Journal of Tropical Medicine and Hygiene · 2017 · 68 citations

Health and Healthcare in Ghana, 1957–2017

Oxford University Press eBooks · 2017 · 28 citations

Efficacy of Artesunate/Amodiaquine in the Treatment of Uncomplicated Malaria among Children in Ghana

American Journal of Tropical Medicine and Hygiene · 2017 · 28 citations

Development and validation of a prediction model for gestational hypertension in a Ghanaian cohort

BMJ Open · 2017 · 25 citations

Prevalence of enteric infections among hospitalized patients in two referral hospitals in Ghana

BMC Research Notes · 2017 · 22 citations

Variations in the quality of malaria-specific antibodies with transmission intensity in a seasonal malaria transmission area of Northern Ghana

PLoS ONE · 2017 · 22 citations

Lack of Geospatial Population Structure Yet Significant Linkage Disequilibrium in the Reservoir of Plasmodium falciparum in Bongo District, Ghana

American Journal of Tropical Medicine and Hygiene · 2017 · 20 citations

Information gaps in surveillance data and effects on the Ghanaian response to the Ebola outbreak in West Africa

Ghana Medical Journal · 2017 · 10 citations

VAR CODE: A NEW MOLECULAR EPIDEMIOLOGY TOOL FOR MONITORING PLASMODIUM FALCIPARUM IN A HIGH TRANSMISSION AREA OF GHANA, WEST AFRICA

American Journal of Tropical Medicine and Hygiene · 2017

Correction

BMJ Open · 2017

EPIDEMIOLOGY OF CHRONIC ASYMPTOMATIC PLASMODIUM FALCIPARUM INFECTIONS AMONG ALL AGES IN AN AREA WITH SEASONAL MALARIA TRANSMISSION IN BONGO DISTRICT, GHANA

American Journal of Tropical Medicine and Hygiene · 2017

Within-host competition and drug resistance in the human malaria parasite Plasmodium falciparum

Proceedings of the Royal Society B Biological Sciences · 2016 · 66 citations

Spatio-Temporal Distribution of Mycobacterium tuberculosis Complex Strains in Ghana

PLoS ONE · 2016 · 53 citations

Detection and characterization of drug-resistant conferring genes in Mycobacterium tuberculosis complex strains: A prospective study in two distant regions of Ghana

Tuberculosis · 2016 · 52 citations

Molecular epidemiology of Mycobacterium africanum in Ghana

BMC Infectious Diseases · 2016 · 50 citations

Antitrypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth

Antimicrobial Agents and Chemotherapy · 2016 · 42 citations

Genetic diversity of Plasmodium falciparum isolates from uncomplicated malaria cases in Ghana over a decade

Parasites & Vectors · 2016 · 41 citations

Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine combinations in the treatment of uncomplicated malaria in two ecological zones in Ghana

Malaria Journal · 2016 · 36 citations

Monitoring malaria using health facility based surveys: challenges and limitations

BMC Public Health · 2016 · 28 citations

Safety and Immunogenicity of EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly in Semi-Immune Adults: A Phase 1, Double-Blinded Placebo Controlled Dosage Escalation Study

PLoS ONE · 2016 · corresponding author · 26 citations

Incidence of medically attended influenza among residents of Shai-Osudoku and Ningo-Prampram Districts, Ghana, May 2013 – April 2015

BMC Infectious Diseases · 2016 · 25 citations

Sentinel surveillance for influenza among severe acute respiratory infection and acute febrile illness inpatients at three hospitals in Ghana

Influenza and Other Respiratory Viruses · 2016 · 23 citations

Measurement of ex vivo ELISpot interferon-gamma recall responses to Plasmodium falciparum AMA1 and CSP in Ghanaian adults with natural exposure to malaria

Malaria Journal · 2016 · 19 citations

Non-malaria fevers in a high malaria endemic area of Ghana

BMC Infectious Diseases · 2016 · 17 citations

Seroprevalence of Antibodies against Plasmodium falciparum Sporozoite Antigens as Predictive Disease Transmission Markers in an Area of Ghana with Seasonal Malaria Transmission

PLoS ONE · 2016 · 16 citations

Clonal types of Toxoplasma gondii among immune compromised and immune competent individuals in Accra, Ghana

Parasitology International · 2016 · 8 citations

The First population structure and comparative genomics analysis of Mycobacterium africanum strains from Ghana reveals higher diversity of Lineage 5

International Journal of Mycobacteriology · 2016 · 5 citations

Additional file 2: Table S2. of Molecular epidemiology of Mycobacterium africanum in Ghana

Figshare · 2016

Author response: Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia

2016

Additional file 3: Table S3. of Genetic diversity of Plasmodium falciparum isolates from uncomplicated malaria cases in Ghana over a decade

Figshare · 2016

Additional file 2: Table S2. of Molecular epidemiology of Mycobacterium africanum in Ghana

Figshare · 2016

Additional file 1: Table S1. of Molecular epidemiology of Mycobacterium africanum in Ghana

Figshare · 2016

Additional file 1: Table S1. of Molecular epidemiology of Mycobacterium africanum in Ghana

Figshare · 2016

New anti-trypanosomal active tetracyclic iridoid isolated from Morinda lucida Benth.

Bioorganic & Medicinal Chemistry Letters · 2015 · 36 citations

Measuring naturally acquired ex vivo IFN-γ responses to Plasmodium falciparum cell-traversal protein for ookinetes and sporozoites (CelTOS) in Ghanaian adults

Malaria Journal · 2015 · 23 citations

Serological evidence of vector and parasite exposure in Southern Ghana: the dynamics of malaria transmission intensity

Parasites & Vectors · 2015 · 20 citations

Procyanidin trimer C1 derived from Theobroma cacao reactivates latent human immunodeficiency virus type 1 provirus

Biochemical and Biophysical Research Communications · 2015 · 16 citations

Measuring regional and district variations in the incidence of pregnancy‐induced hypertension in Ghana: challenges, opportunities and implications for maternal and newborn health policy and programmes

Tropical Medicine & International Health · 2015 · 10 citations

Determination of the absolute configuration of the novel anti-trypanosomal iridoid molucidin isolated from Morinda lucida by X-ray analysis

Tetrahedron Letters · 2015 · 6 citations

CCDC 1419523: Experimental Crystal Structure Determination

The Cambridge Structural Database · 2015

A SURVEY OF THE RESERVOIR OF MOLECULAR MARKERS OF PLASMODIUM FALCIPARUM ANTIMALARIAL DRUG RESISTANCE FROM A HIGH TRANSMISSION SETTING IN BONGO DISTRICT, GHANA

American Journal of Tropical Medicine and Hygiene · 2015

Corrigendum to “Procyanidin trimer C1 derived from Theobroma cacao reactivates latent human immunodeficiency virus type 1 provirus” [Biochem. Biophys. Res. Commun. 459 (2) (3 April 2015) 288–293]

Biochemical and Biophysical Research Communications · 2015

Reappraisal of known malaria resistance loci in a large multicenter study

Nature Genetics · 2014 · 243 citations

Chronic non-communicable diseases and the challenge of universal health coverage: insights from community-based cardiovascular disease research in urban poor communities in Accra, Ghana

BMC Public Health · 2014 · 142 citations

Dynamics of the Antibody Response to Plasmodium falciparum Infection in African Children

The Journal of Infectious Diseases · 2014 · 139 citations

Anti-sporozoite antibodies as alternative markers for malaria transmission intensity estimation

Malaria Journal · 2014 · 37 citations

Patterns of cardiovascular disease mortality in Ghana: a 5-year review of autopsy cases at Korle-Bu Teaching Hospital.

PubMed · 2014 · 32 citations

Biochemical and Hematologic Parameters for Children in the Middle Belt of Ghana

American Journal of Tropical Medicine and Hygiene · 2014 · 25 citations

Anti-Trypanosomal Activity of Diarylheptanoids Isolated from the Bark ofAlnus japonica

The American Journal of Chinese Medicine · 2014 · 18 citations

Malaria control in Africa: progress but still much to do

The Lancet · 2014 · 14 citations

The Efficacy Of Three Compounds Isolated From CVP005B Leaves Against Laboratory And Field Strains Of Leishmania spp.

2014

Isolation of Novel Anti-Trypanosomal Compounds From Morinda Lucida Leaf Extract

2014

Joint Research Project on Infectious Diseases in West-African Subregion

Journal of Disaster Research · 2014

Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

PLoS Genetics · 2013 · 131 citations

Increased pfmdr1 gene copy number and the decline in pfcrt and pfmdr1 resistance alleles in Ghanaian Plasmodium falciparum isolates after the change of anti-malarial drug treatment policy

Malaria Journal · 2013 · 89 citations

Placental Malaria and the Risk of Malaria in Infants in a High Malaria Transmission Area in Ghana: A Prospective Cohort Study

The Journal of Infectious Diseases · 2013 · 63 citations

A SYBR Green 1-based in vitro test of susceptibility of Ghanaian Plasmodium falciparum clinical isolates to a panel of anti-malarial drugs

Malaria Journal · 2013 · 39 citations

Impact of treating young children with antimalarials with or without antibiotics on morbidity: a cluster-randomized controlled trial in Ghana

International Health · 2013 · 7 citations

PP081. Predictors of pregnancy induced hypertension in an urban low resource setting

Pregnancy Hypertension · 2013 · 2 citations

Therapeutic efficacy of artemether-lumefantrine combination in the treatment of uncomplicated malaria among children under five years of age in three ecological zones in Ghana

Malaria Journal · 2012 · 42 citations

Surveillance of Molecular Markers of Plasmodium falciparum Resistance to Sulphadoxine-Pyrimethamine 5 Years after the Change of Malaria Treatment Policy in Ghana

American Journal of Tropical Medicine and Hygiene · 2012 · 36 citations

A Community-Wide Study of Malaria Reduction: Evaluating Efficacy and User-Acceptance of a Low-Cost Repellent in Northern Ghana

American Journal of Tropical Medicine and Hygiene · 2012 · 24 citations

Intermittent preventive treatment for children (IPTC) combined with timely home treatment for malaria control

Malaria Journal · 2012 · 3 citations