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Dominic Edoh

University of Ghana

54 publications · 1,009 citations

Malaria Research and ControlParasites and Host InteractionsMosquito-borne diseases and controlGlobal Maternal and Child HealthEthnobotanical and Medicinal Plants Studies

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Dominic Edoh is a researcher whose work spans molecular parasitology, epidemiology, and ethnopharmacology. Initially focused on the molecular genetics of malaria parasites and snail control strategies, Edoh later expanded into epidemiological studies of parasitic infections in Ghana and the evaluation of medicinal plants for treating tropical diseases.

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What is the comparative efficacy and cost-effectiveness of the one-step 75g OGTT versus the two-step (50g GCT followed by 100g OGTT) diagnostic approach in preventing adverse maternal and neonatal outcomes?

Why this gap exists: While Abstract [7] compares diagnostic criteria and Abstract [4] compares 75g and 100g OGTTs, the retrieved evidence lacks direct, comparative studies on the cost-effectiveness and relative efficacy of the one-step versus two-step *approaches* in preventing adverse outcomes, leaving the specific question unresolved.

Sources

  1. Glucose Intolerance after a Recent History of Gestational Diabetes Based on the 2013 WHO Criteria — PLoS ONE, 2016
  2. A Multicenter, Randomized Trial of Treatment for Mild Gestational Diabetes — New England Journal of Medicine, 2009
  3. Standards of Medical Care in Diabetes—2013 — Diabetes Care, 2012
  4. An Update on Screening Strategies for Gestational Diabetes Mellitus: A Narrative Review — Diabetes Metabolic Syndrome and Obesity, 2021
  5. Comparison between 75-g and 100-g oral glucose tolerance tests using international association of diabetes and pregnancy study group one-step diagnostic threshold to detect gestational diabetes mellitus — Frontiers in Endocrinology, 2025
  6. Large language models for generating longitudinal synthetic data in low-risk pregnancy care. — Data in brief, 2026
  7. Effects of physical activity and diet in pregnancy to prevent gestational diabetes: an individual participant data (IPD) meta-analysis on the differential effects of interventions with economic evaluation. — Health technology assessment (Winchester, England), 2026
  8. 187-OR: Randomized Clinical Trial of the IADPSG vs. Carpenter Coustan Criteria for Diagnosis of Gestational Diabetes Mellitus — Diabetes, 2020
  9. Prevalence of gestational diabetes mellitus and results of the screening tests at a tertiary referral center: A cross-sectional study. — Diabetes & metabolic syndrome, 2019
  10. Gestational Diabetes in Somali Women: Neglected Risks for Maternal and Neonatal Health. — International journal of women's health, 2026

What is the comparative efficacy of household water treatment interventions versus improved water source infrastructure in reducing stunting among children under five in low- and middle-income countries?

Why this gap exists: While the retrieved literature confirms associations between water quality and child growth (e.g., Abstracts 2, 5, 8), no study directly compares the efficacy of household water treatment interventions against improved water source infrastructure for reducing stunting, leaving the specific comparative question unresolved.

Sources

  1. Determinants of stunting in Indonesian children: evidence from a cross-sectional survey indicate a prominent role for the water, sanitation and hygiene sector in stunting reduction — BMC Public Health, 2016
  2. Early estimates of the indirect effects of the COVID-19 pandemic on maternal and child mortality in low-income and middle-income countries: a modelling study — The Lancet Global Health, 2020
  3. Effects of water quality, sanitation, handwashing, and nutritional interventions on diarrhoea and child growth in rural Kenya: a cluster-randomised controlled trial — The Lancet Global Health, 2018
  4. Effects of Water Pollution on Human Health and Disease Heterogeneity: A Review — Frontiers in Environmental Science, 2022
  5. Associated factors with malnutrition among children under-5 years old in Somaliland: evidence from Somaliland health and demographic survey of 2020. — BMC public health, 2026
  6. Safe Drinking Water and Its Impact on Children's Growth and Development: A Systematic Review. — International journal of environmental research and public health, 2026
  7. Modelling the impact of dietary diversity on child nutrition in Pakistan: a machine learning analysis with Shapley Additive exPlanations and Boruta interpretability. — Journal of global health, 2026
  8. Effectiveness of interventions to improve drinking water, sanitation, and handwashing with soap on risk of diarrhoeal disease in children in low-income and middle-income settings: a systematic review and meta-analysis — The Lancet, 2022
  9. Effect of Household Source of Drinking Water on Malnutrition among under Five Children in Ethiopia: Systematic Review and Meta-Analysis — 2026
  10. Water Bridging Dynamics of Polymerase Chain Reaction in the Gauge Theory Paradigm of Quantum Fields — Water 2017, 9, 339, 2018

What are the specific long-term treatment strategies required to mitigate the risk of developing chronic non-communicable diseases in children born to mothers with gestational diabetes mellitus?

Why this gap exists: While the retrieved literature consistently establishes that maternal gestational diabetes mellitus (GDM) increases the long-term risk of cardiometabolic diseases in offspring [1][2][3], it focuses primarily on pathogenesis and risk association rather than defining specific, evidence-based long-term treatment strategies for the children to mitigate these risks.

Sources

  1. Diagnosis and Classification of Diabetes Mellitus — Diabetes Care, 2010
  2. A Clinical Update on Gestational Diabetes Mellitus — Endocrine Reviews, 2022
  3. Maternal Diabetes and Risk of Early-Onset Cardiovascular Diseases in Offspring. — JAMA cardiology, 2026
  4. Gestational diabetes as an inter-generational cardiometabolic risk factor: spotlight on emerging exerkines. — Cardiovascular diabetology, 2026
  5. Gestational diabetes: from pathogenesis to therapeutic intervention. — Diabetology & metabolic syndrome, 2026
  6. 2. Classification and Diagnosis of Diabetes:<i>Standards of Medical Care in Diabetes—2022</i> — Diabetes Care, 2021
  7. Maternal congenital heart disease and risk of child developmental vulnerability in early school age: A population-based cohort study. — PLoS medicine, 2026
  8. Gestational Diabetes in Somali Women: Neglected Risks for Maternal and Neonatal Health. — International journal of women's health, 2026
  9. Gestational Diabetes and Obesity: Immediate and Late Sequelae for Offspring. — Children (Basel, Switzerland), 2025
  10. Gestational Diabetes Mellitus: Diagnostic Approaches and Maternal-Offspring Complications — Diabetes & Metabolism Journal, 2022

How do specific maternal microbiota profiles (gut, oral, or vaginal) during gestation correlate with the development of gestational diabetes mellitus (GDM) and subsequent long-term metabolic health in offspring?

Why this gap exists: While recent reviews [8] confirm GDM alters maternal gut microbiota and neonatal health, and older studies [0] note dysbiosis across maternal sites, the retrieved evidence lacks direct, longitudinal studies correlating specific gestational maternal microbiota profiles with the *long-term* metabolic health of offspring, leaving the core question unresolved.

Sources

  1. Dysbiosis of maternal and neonatal microbiota associated with gestational diabetes mellitus — Gut, 2018
  2. Dysbiosis of the gut microbiota in disease — Microbial Ecology in Health and Disease, 2015
  3. Temporal development of the gut microbiome in early childhood from the TEDDY study — Nature, 2018
  4. Microbiota in health and diseases — Signal Transduction and Targeted Therapy, 2022
  5. Maternal Gestational Diabetes Mellitus and Congenital Heart Disease in Offspring: A Meta-Analysis — Hormone and Metabolic Research, 2024
  6. Perinatal phlorizin alleviates maternal high-fat diet-induced metabolic syndrome in female mouse offspring and is associated with modulation of the gut microbiota. — Frontiers in nutrition, 2026
  7. Offspring long-term infectious morbidity following pregnancies with cervical cerclage. — Archives of gynecology and obstetrics, 2026
  8. Interaction between microbiota and immunity in health and disease — Cell Research, 2020
  9. Gestational diabetes mellitus and maternal-infant microbiome axis: mechanistic insights and therapeutic interventions. — Journal of translational medicine, 2026
  10. Microbes in the Moonlight: How the Gut Microbiota Influences Sleep — arXiv preprint, 2025

To what extent do changes in the maternal microbiota (gut, oral, or vaginal) during pregnancy mediate the relationship between maternal perinatal anxiety/depression and the neurodevelopmental outcomes of the offspring?

Why this gap exists: While recent studies confirm associations between maternal mental health and microbiota composition (Abstract 5, 8) and suggest the microbiome-gut-brain axis influences neurodevelopment (Abstract 0, 2), the retrieved evidence does not contain studies that directly test the mediating role of maternal microbiota changes between perinatal anxiety/depression and offspring neurodevelopmental outcomes.

Sources

  1. Parental microbiome programming of early-life neurodevelopment: multi-niche contributions through the microbiome-gut-brain axis. — Gut microbes, 2026
  2. Dysbiosis of the gut microbiota in disease — Microbial Ecology in Health and Disease, 2015
  3. Stress during pregnancy alters temporal and spatial dynamics of the maternal and offspring microbiome in a sex-specific manner — Scientific Reports, 2017
  4. The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication — Frontiers in Endocrinology, 2020
  5. Ultra-processed food consumption across early life: implications for pediatric health and disease risk. — Frontiers in nutrition, 2026
  6. Mental health in early pregnancy: Interplay of objectively measured lifestyles, gut microbiota, and metabolomics. — iScience, 2026
  7. The impact of maternal high-fat diet on offspring neurodevelopment — Frontiers in Neuroscience, 2022
  8. Maternal education and offspring birthweight for gestational age: the mediating effect of smoking during pregnancy — arXiv preprint, 2020
  9. Is Gut Microbiota Altered in Depression and Anxiety? — 2025
  10. Vaginal Microbiota: A Critical Component of Reproductive Health and Pregnancy Outcomes — Vaginal Microbiota: A Critical Component of Reproductive Health and Pregnancy Outcomes, 2025

How do specific policy frameworks regarding social protection and food systems in low-income countries moderate the projected increase in child wasting and maternal undernutrition caused by economic shocks like the COVID-19 pandemic?

Why this gap exists: While the retrieved literature confirms the projected increase in child wasting and maternal undernutrition due to COVID-19 disruptions [0] and explores general concepts of food system resilience [2] and social protection [3], no study directly quantifies how specific policy frameworks moderate these projected outcomes, leaving the core interaction unresolved.

Sources

  1. Early estimates of the indirect effects of the COVID-19 pandemic on maternal and child mortality in low-income and middle-income countries: a modelling study — The Lancet Global Health, 2020
  2. Biofortification as a sustainable strategy to address micronutrient malnutrition in South Asia. — Journal of health, population, and nutrition, 2025
  3. Resilience of local food systems and links to food security – A review of some important concepts in the context of COVID-19 and other shocks — Food Security, 2020
  4. Resilience and Recovery in the Informal Economy: Social Networks, Social Protection, and Adaptive Strategies Among Post-COVID Workers in Bangladesh. — Public health challenges, 2026
  5. Malnutrition at a Crossroads: The Impact of Pandemic, Climate Change, and War on Tigray’s Children Malnutrition — 2026
  6. Economic Shocks, Inequality and Poverty: The Need for Safety Nets — 1998
  7. Lessons from low-to middle-income countries on the development of child protection systems — The Development of Child Protection Systems and Practice in Low- to Middle-Income Countries, 2025
  8. Drivers of Stunting Reduction in Yogyakarta, Indonesia: A Case Study. — International journal of environmental research and public health, 2022
  9. Inequality, mobility and the financial accumulation process: A computational economic analysis — Journal of Economic Interaction and Coordination (2020), online, 2019
  10. The Role of Agriculture in Ensuring Food Security in Developing Countries: Considerations in the Context of the Problem of Sustainable Food Production — Sustainability, 2020

Publications

Parasitic Infection, Condition Factor, and Length-Weight Relationship of Sarotherodon melanotheron in Brackish and Freshwater Bodies in Coastal Accra, Ghana.

Research Square · 2025

Antiplasmodial and Genotoxic Study of Selected Ghanaian Medicinal Plants

Evidence-based Complementary and Alternative Medicine · 2020 · 10 citations

Epidemiology of Hookworm Infection in Kintampo North Municipality, Ghana: Patterns of Malaria Coinfection, Anemia, and Albendazole Treatment Failure

UNC Libraries · 2020

<i>In vitro</i> antiprotozoan activity and mechanisms of action of selected <scp>G</scp>hanaian medicinal plants against <i>Trypanosoma</i>, <i>Leishmania</i>, and <i>Plasmodium</i> parasites

Phytotherapy Research · 2018 · 62 citations

Antitrypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth

Antimicrobial Agents and Chemotherapy · 2016 · 42 citations

Antioxidant and antimicrobial capacities of ethanolic extract of <i>Pergularia daemia</i> leaves: a possible substitute in diabetic management

Journal of Complementary and Integrative Medicine · 2016 · 4 citations

New anti-trypanosomal active tetracyclic iridoid isolated from Morinda lucida Benth.

Bioorganic & Medicinal Chemistry Letters · 2015 · 36 citations

Antiproliferative and Pro-Apoptotic Activity of Diarylheptanoids Isolated from the Bark of <i>Alnus japonica</i> in Human Leukemia Cell Lines

The American Journal of Chinese Medicine · 2015 · 22 citations

Shrinkage of Prostate and Improved Quality of Life: Management of BPH Patients with <i>Croton membranaceus</i> Ethanolic Root Extract

Evidence-based Complementary and Alternative Medicine · 2015 · 17 citations

Procyanidin trimer C1 derived from Theobroma cacao reactivates latent human immunodeficiency virus type 1 provirus

Biochemical and Biophysical Research Communications · 2015 · 16 citations

High Levels of IL-10 and CD4+CD25hi+ Treg Cells in Endemic Burkitt’s Lymphoma Patients

Biomedicines · 2015 · 8 citations

Determination of the absolute configuration of the novel anti-trypanosomal iridoid molucidin isolated from Morinda lucida by X-ray analysis

Tetrahedron Letters · 2015 · 6 citations

A randomized double-blind study evaluating the safety and effectiveness of a Ghanaian polyherbal product for the management of superficial mycoses

Journal of Herbal Medicine · 2015 · 5 citations

Screening of Ageratum conyzoides Linn. and Alchornea cordifolia (Schumach. &amp; Thonn.) Extracts for Antibacterial Activity

European Journal of Medicinal Plants · 2015 · 3 citations

DETERMINATION OF THE RUTIN, QUERCETIN AND KAEMPFEROL CONTENTS IN A GHANAIAN POLYHERBAL FORMULATION (EAF-2011) AND ITS RAW MATERIALS USING A SIMULTANEOUS RP-HPLC METHOD

International Journal of Pharmaceutical Sciences and Drug Research · 2015 · 3 citations

Corrigendum to “Procyanidin trimer C1 derived from Theobroma cacao reactivates latent human immunodeficiency virus type 1 provirus” [Biochem. Biophys. Res. Commun. 459 (2) (3 April 2015) 288–293]

Biochemical and Biophysical Research Communications · 2015

Bioassay-Guided Discovery of Antibacterial Agents: In vitro Susceptibility of Multi-drug Resistant Staphylococcus aureus to Psidium guajava Linn Extracts

European Journal of Medicinal Plants · 2015

CCDC 1419523: Experimental Crystal Structure Determination

The Cambridge Structural Database · 2015

Anti-Trypanosomal Activity of Diarylheptanoids Isolated from the Bark of<i>Alnus japonica</i>

The American Journal of Chinese Medicine · 2014 · 18 citations

Isolation of Novel Anti-Trypanosomal Compounds From Morinda Lucida Leaf Extract

2014

The Efficacy Of Three Compounds Isolated From CVP005B Leaves Against Laboratory And Field Strains Of Leishmania spp.

2014

(untitled)

International Journal of Pharmaceutical Sciences and Research · 2014

High Plasma Levels of Soluble Intercellular Adhesion Molecule (ICAM)-1 Are Associated with Cerebral Malaria

PLoS ONE · 2013 · 39 citations

ANTIHYPERGLYCAEMIC ACTIVITY OF ETHANOLIC EXTRACT OF THE STEM OF ADENIA LOBATA ENGL (PASSIFLORACEAE)

2013 · 13 citations

Quality and safety evaluation of a Ghanaian polyherbal product EAF-2011 for the management of superficial mycoses

International Journal of Medicine and Biomedical Research · 2013 · 5 citations

Prospects of<i>Croton membranaceus</i>for Prostate Health

ACS symposium series · 2013 · 4 citations

(untitled)

International Journal of Pharmaceutical Sciences and Research · 2013

Dynamics of pyrimethamine-resistant P. falciparum parasites in sulphadoxine-pyrimethamine treated Tanzanian children.

PubMed · 2012

Epidemiology of Hookworm Infection in Kintampo North Municipality, Ghana: Patterns of Malaria Coinfection, Anemia, and Albendazole Treatment Failure

American Journal of Tropical Medicine and Hygiene · 2011 · 123 citations

Urinary schistosomiasis among adults in the Volta Basin of Ghana: prevalence, knowledge and practices.

The Journal of Tropical Medicine and Parasitology · 2011 · 27 citations

Sero-epidemiology of toxoplasmosis amongst pregnant women in the greater Accra region of Ghana

Ghana Medical Journal · 2010 · 89 citations

Parasitic infections and anaemia during pregnancy in the Kassena-Nankana district of Northern Ghana.

Journal of Public Health and Epidemiology · 2010 · 29 citations

Investigation of the Risk of Infection of Urinary Schistosomiasis at Mahem and Galilea Communities in the Greater Accra Region of Ghana

West African Journal of Applied Ecology · 2010 · 19 citations

Internalisation of Microbes in Vegetables: Microbial Load of Ghanaian Vegetables and the Relationship with Different Water Sources of Irrigation

Pakistan Journal of Biological Sciences · 2010 · 16 citations

Intestinal Parasites of the Grasscutter (Thryonomys swinderianus Temminck 1827) from the Kwaebibirem District of the Eastern Region of Ghana

West African Journal of Applied Ecology · 2010 · 7 citations

Chemoreception niche of &lt;i&gt;Bulinus globosus&lt;/i&gt;, as an aid to snail control

International Journal of Natural and Applied Sciences · 2010

Plasmodium and intestinal helminths distribution among pregnant women in the Kassena-Nankana District of Northern Ghana

Journal of Entomology and Nematology · 2009 · 13 citations

COMPARISON OF ANTIBIOTIC RESISTANCE PATTERNS BETWEEN LABORATORIES IN ACCRA EAST, GHANA

African Journal of Science and Technology · 2007 · 7 citations

Mutations in Plasmodium falciparum Chloroquine Resistance Transporter and Multidrug Resistance Genes, and Treatment Outcomes in Ghanaian Children with Uncomplicated Malaria

Journal of Tropical Pediatrics · 2006 · 32 citations

Fetal hemoglobin during infancy and in sickle cell adults.

PubMed · 2006 · 31 citations

Experimental control of<i>Biomphalaria pfeifferi</i>, the intermediate host of<i>Schistosoma mansoni</i>, by the ampullariid snail<i>Lanistes varicus</i>

Annals of Tropical Medicine and Parasitology · 2005 · 10 citations

A Community-based feasibility study of National Health Insurance scheme in Ghana

African Journal of Health Sciences · 2004 · 10 citations

Rapid assessment of a National tuberculosis control programme in Eastern Ghana

African Journal of Health Sciences · 2004 · 1 citations

Influence of biomedical sciences on National Health Insurance scheme in Ghana

African Journal of Health Sciences · 2004

6. Multiple Plasmodium falciparum infections in Tanzanian infants

Transactions of the Royal Society of Tropical Medicine and Hygiene · 1999 · 65 citations

9. Effect of insecticide-treated bed nets on haemoglobin values, prevalence and multiplicity of infection with Plasmodium falciparum in a randomized controlled trial in Tanzania

Transactions of the Royal Society of Tropical Medicine and Hygiene · 1999 · 54 citations

Comparison of Three Methods for Detection of Plasmodium Oocysts in Wild-Caught Mosquitoes

International Journal of Tropical Insect Science · 1998 · corresponding author

PCR amplification of DNA from malaria parasites on fixed and stained thick and thin blood films

Transactions of the Royal Society of Tropical Medicine and Hygiene · 1997 · 27 citations

Pyrimethamine-Resistant Plasmodium Falciparum Parasites among Tanzanian Children: a Facility-Based Study using the Polymerase Chain Reaction

American Journal of Tropical Medicine and Hygiene · 1997 · 13 citations

Polymerase Chain Reaction Used To Describe Larval Habitat Use by Anopheles gambiae Complex (Diptera: Culicidae) in the Environs of Ifakara, Tanzania

Journal of Medical Entomology · 1996 · corresponding author · 64 citations

Does chloroquine treatment influence the distribution of pyrimethamine-resistant P. falciparum parasites in the field?

PubMed · 1996

Rejoinder: The use of PCR in the field

Parasitology Today · 1995 · corresponding author · 1 citations

Activity of U-snRNA genes with modified placement of promoter elements in transfected protoplasts and stably transformed tobacco

Nucleic Acids Research · 1993 · 5 citations

Structure and expression of the U5 snRNA gene of Arabidopsis thaliana. Conserved upstream sequence elements in plant U-RNA genes

Nucleic Acids Research · 1988 · 54 citations