Navrongo Health Research Centre
53 publications · 511 citations · ORCID 0000-0003-1871-8048
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James Abugri is a researcher focused on infectious diseases, particularly malaria, and non-communicable diseases such as diabetes and cardiovascular health within the Ghanaian context. Abugri's work spans molecular studies of *Plasmodium falciparum* drug resistance and invasion mechanisms to clinical analyses of early-onset diabetes and gestational diabetes mellitus. Additionally, Abugri contributes to research on environmental health, phytochemistry, and the immunology of pregnancy-associated malaria.
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Why this gap exists: While recent reviews [8] confirm GDM alters maternal gut microbiota and neonatal health, and older studies [0] note dysbiosis across maternal sites, the retrieved evidence lacks direct, longitudinal studies correlating specific gestational maternal microbiota profiles with the *long-term* metabolic health of offspring, leaving the core question unresolved.
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Why this gap exists: While the retrieved literature consistently establishes that maternal gestational diabetes mellitus (GDM) increases the long-term risk of cardiometabolic diseases in offspring [1][2][3], it focuses primarily on pathogenesis and risk association rather than defining specific, evidence-based long-term treatment strategies for the children to mitigate these risks.
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Why this gap exists: While a 2023 network meta-analysis [6] synthesizes general efficacy and adherence data for LTBI regimens, the retrieved evidence lacks direct comparative studies specifically focused on high-burden, low-resource settings, leaving the specific constraints of these environments unresolved.
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Why this gap exists: While recent studies confirm associations between maternal mental health and microbiota composition (Abstract 5, 8) and suggest the microbiome-gut-brain axis influences neurodevelopment (Abstract 0, 2), the retrieved evidence does not contain studies that directly test the mediating role of maternal microbiota changes between perinatal anxiety/depression and offspring neurodevelopmental outcomes.
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Why this gap exists: While Abstract [7] compares diagnostic criteria and Abstract [4] compares 75g and 100g OGTTs, the retrieved evidence lacks direct, comparative studies on the cost-effectiveness and relative efficacy of the one-step versus two-step *approaches* in preventing adverse outcomes, leaving the specific question unresolved.
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Why this gap exists: While abstracts [6] and [8] compare digital and in-person delivery during the pandemic, they are set in high-income contexts (Spain, unspecified high-income), and abstract [7] focuses on LMICs but lacks a comparative digital vs. in-person design, leaving the specific question of comparative efficacy in LMICs unresolved.
Sources
Antibody reactivity to the VAR2CSA DBL5 domain among pregnant women in Northern Ghana
BMC Infectious Diseases · 2026 · corresponding author
Clinical Epidemiology and Global Health · 2026 · corresponding author
BioMed Research International · 2025 · 6 citations
Beverages · 2025 · 5 citations
PLoS ONE · 2025 · corresponding author · 2 citations
Research Square · 2025
Research Square · 2025
Early‐Onset Diabetes in Ghana's Upper East Region—Insights From Hospital Data
Endocrinology Diabetes & Metabolism · 2025
BMC Infectious Diseases · 2025
Endocrinology Diabetes & Metabolism · 2024 · 15 citations
Soil quality and heavy metal contamination in an open dumpsite in Navrongo, Ghana
Environmental Monitoring and Assessment · 2024 · 8 citations
Computation · 2024 · 3 citations
Traditional Uses, Phytochemicals, and Biological Properties of Saba Senegalensis
SSRN Electronic Journal · 2024
Co-infection of Plasmodium falciparum and Schistosoma mansoni is associated with anaemia
Malaria Journal · 2023 · 13 citations
Frontiers in Drug Discovery · 2023 · corresponding author · 11 citations
Early-onset diabetes in Africa: A mini-review of the current genetic profile
European Journal of Medical Genetics · 2023 · 3 citations
Drugs, Vaccines and Druggable Targets of Salmonella Typhi
Preprints.org · 2023 · 1 citations
Malaria Journal · 2023
Preprints.org · 2023
SSRN Electronic Journal · 2023
Recapitulating potential environmental and industrial applications of biomass wastes
Journal of Material Cycles and Waste Management · 2022 · 24 citations
Heliyon · 2022 · corresponding author · 15 citations
Microbiota in a long survival discourse with the human host
Archives of Microbiology · 2022 · corresponding author · 11 citations
Exploratory Research and Hypothesis in Medicine · 2022 · 2 citations
Microbiota in a Long Survival Discourse with the Human Host
Preprints.org · 2022 · corresponding author · 2 citations
HAL (Le Centre pour la Communication Scientifique Directe) · 2022 · 1 citations
bioRxiv (Cold Spring Harbor Laboratory) · 2022 · corresponding author
Wellcome Open Research · 2021 · 43 citations
Journal of Applied Biotechnology & Bioengineering · 2021 · corresponding author · 3 citations
Preprints.org · 2021 · 3 citations
Preprints.org · 2021 · corresponding author · 2 citations
Preprints.org · 2021 · 1 citations
Preprints.org · 2021 · corresponding author · 1 citations
Pharmacy & Pharmacology International Journal · 2021
Machine learning approaches classify clinical malaria outcomes based on haematological parameters
BMC Medicine · 2020 · 44 citations
Intrinsic multiplication rate variation and plasticity of human blood stage malaria parasites
Communications Biology · 2020 · 31 citations
Scientific African · 2020 · corresponding author · 14 citations
Machine learning approaches classify clinical malaria outcomes based on haematological parameters
medRxiv · 2020 · 5 citations
International Journal of Microbiology · 2020 · 2 citations
Intrinsic multiplication rate variation and plasticity of human blood stage malaria parasites
bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 1 citations
Open MIND · 2020
AAS Open Research · 2018 · 16 citations
AAS Open Research · 2018 · 13 citations
Malaria Journal · 2017 · 41 citations
Comparison of malaria diagnostic methods in four hospitals in the Volta region of Ghana
PubMed · 2016 · 21 citations
BMC Genomics · 2015 · 48 citations
The Journal of Infectious Diseases · 2015 · 37 citations
BMC Research Notes · 2014 · corresponding author · 9 citations
Profiles of HIV-Affected Households in Ghana
Health · 2014 · 1 citations
Predictors of fetal anemia and cord blood malaria parasitemia among newborns of HIV-positive mothers
BMC Research Notes · 2013 · 54 citations